2-Chloro-4-methyl-3-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23056-39-5 |
| Product name | 2-Chloro-4-methyl-3-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Chloro-4-methyl-3-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Chloro-4-methyl-3-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Chloro-4-methyl-3-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for synthesizing novel neonicotinoid insecticides (e.g., flupyradifurone) | Used to construct the neonicotinoid molecular scaffold via nucleophilic substitution with amine compounds such as N-methylpiperazine |
| Pharmaceuticals | Used to synthesize nitrogen-containing heterocyclic compounds with antitumor and antiviral activity | Serves as a starting material in multistep organic synthesis, e.g., cyclization with hydrazide compounds to prepare triazolopyrimidine derivatives |
| Materials Science | Building block for functionalized organic semiconductor materials | Integrated into conjugated polymer backbones via Suzuki or Heck coupling reactions to tune optoelectronic properties |
Manufacturing Quality Control of 2-Chloro-4-methyl-3-nitropyridine
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of visible impurities by eye, ensuring compliance with pharmacopoeial or company standards. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Record the infrared absorption spectrum of the sample and compare it with that of the reference standard to confirm characteristic functional groups (e.g., nitro group, chloropyridine ring); HPLC: Under specified chromatographic conditions, the retention time of the main peak of the sample matches that of the reference standard. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Using a reversed-phase C18 column with methanol-water or acetonitrile-water as the mobile phase and a UV detector (typically at 254 nm or set at the maximum absorption wavelength), the content of the active ingredient is calculated by the external standard method to ensure purity meets requirements (e.g., ≥98.0%). |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using the same conditions as for assay or a gradient elution program, separate and detect potential process-related impurities (e.g., unreacted starting materials, by-products, degradation products). Individual impurity levels are controlled using the area normalization method or the main component self-reference method with correction factors. |
| Water Content | Karl Fischer Titration | Quantify water content based on the stoichiometric reaction between water in the sample and Karl Fischer reagent, using either coulometric or volumetric titration. Controls the degree of dryness (typically ≤0.5%). |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection into a gas chromatograph equipped with a polar or non-polar capillary column and an FID detector to determine residual organic solvents from manufacturing (e.g., toluene, dichloromethane, methanol), ensuring compliance with ICH Q3C limits. |
| Melting Point | Capillary Melting Point Method | Pack the sample into a melting point capillary tube and heat in a melting point apparatus at a specified rate. Record the temperature range from initial melting to complete melting and compare with the standard value (e.g., literature value approximately 78–82 °C) to assess purity. |
| pH (if prepared as a solution) | pH Meter Method | Dissolve the sample in water to a specified concentration (e.g., 1%), then measure the pH using a calibrated pH meter to evaluate the presence of acidic or basic impurities. |
Technical Specifications of 2-Chloro-4-methyl-3-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Chloro-4-methyl-3-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Chloro-4-methyl-3-nitropyridine
Safety Information of 2-Chloro-4-methyl-3-nitropyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-Chloro-4-methyl-3-nitropyridine
Industrial 2-Chloro-4-methyl-3-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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