2-CHLORO-5-NITROACETOPHENONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23082-50-0 |
| Product name | 2-CHLORO-5-NITROACETOPHENONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-CHLORO-5-NITROACETOPHENONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-CHLORO-5-NITROACETOPHENONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-CHLORO-5-NITROACETOPHENONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Pharmaceutical Intermediate | Serves as a key raw material for constructing the heterocyclic core of quinolone antibacterial agents (e.g., ciprofloxacin) and other antimicrobial compounds. |
| Pharmaceutical Industry | Chemical Synthesis Reagent | Leverages its reactive methylene group to introduce chlorophenyl and nitro functional groups via substitution reactions, enabling construction of specific drug molecule scaffolds. |
| Agrochemical Industry | Agrochemical Intermediate | Used in synthesizing active ingredients of insecticides or fungicides containing nitro and chloro substituents. |
| Dye Industry | Dye Intermediate | Functions as a coupling component or diazo component precursor in azo dye synthesis to produce yellow- or orange-shade dyes. |
| Organic Synthesis | Organic Building Block | Employed in diverse chemical transformations—including nitro group reduction, chloro substitution, and carbonyl condensation—to prepare more complex organic compounds. |
Manufacturing Quality Control of 2-CHLORO-5-NITROACETOPHENONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., starting materials, intermediates, degradation products) using gradient HPLC-UV against qualified reference standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., acetone, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine water content by stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Organic Volatile Impurities | GC-MS | Identification and semi-quantification of unknown volatile impurities using mass spectral library matching and selected ion monitoring. |
| Acid Value | Acid-Base Titration | Titration with standardized KOH solution to quantify acidic impurities (e.g., carboxylic acids) using phenolphthalein indicator. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry dispersion mode using Mie scattering theory. |
Technical Specifications of 2-CHLORO-5-NITROACETOPHENONE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 72–76°C |
| Total Impurities | <=2.0% (GC-MS) |
| Single Impurity | <=0.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-CHLORO-5-NITROACETOPHENONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-CHLORO-5-NITROACETOPHENONE
Packaging of 2-CHLORO-5-NITROACETOPHENONE
Industrial 2-CHLORO-5-NITROACETOPHENONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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