China Factory Direct
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| CAS number | 23165-29-9 |
| Product name | 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as a synthetic intermediate to prepare drug molecules containing a trifluoromethylphenyl moiety, such as anti-inflammatory, antitumor, or central nervous system-active compounds | Introduced via nucleophilic addition or cyclization to incorporate the isothiocyanate group, enabling construction of heterocyclic or urea derivatives |
| Agricultural Chemicals | Used to synthesize fluorinated agrochemicals or plant growth regulators with biological activity | Condensed with amine compounds to generate thiourea derivatives, serving as key structural units in active molecule synthesis |
| Organic Synthesis | Used as a versatile synthon to construct trifluoromethyl aryl thioureas, thiazoles, and other heterocyclic compounds | Reacted with primary amines, hydrazines, or other nucleophiles via the isothiocyanate group to form C–S or C–N bonds |
| Materials Science | Used to prepare fluorinated functional materials, such as liquid crystal monomers or high-refractive-index polymer precursors | Fluoroaryl isothiocyanate structural units incorporated via step-growth polymerization or click chemistry |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water content via electrochemical or stoichiometric reaction. |
| Acid Value | Acid-Base Titration | Titration with standardized potassium hydroxide solution in alcoholic medium to quantify acidic impurities by neutralization. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion using inductively coupled plasma optical emission spectrometry for total metal content. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing of sample at 600-700 C. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid using calibrated capillary method per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard white background under controlled lighting conditions. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution to detect chiral impurities or enantiomeric excess. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution using Mie scattering theory with laser diffraction instrument. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 45–49°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.