China Factory Direct
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| CAS number | 232276-00-5 |
| Product name | Ethyl (S)-2-aMino-3-(4-broMophenyl) propanoate hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a chiral intermediate in the synthesis of targeted therapeutics or peptide compounds | Prepared via asymmetric synthesis or enzymatic resolution; employed in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) |
| Chemical Research | Used to construct model compounds or probe molecules containing bromoaryl amino acid structures | Bromophenyl side chains are introduced using organic synthesis methods such as esterification and cross-coupling of halogenated aromatic compounds |
| Biotechnology | Used as a non-canonical amino acid in protein engineering or metabolic labeling studies | Incorporated into polypeptide chains via genetic code expansion or chemical modification |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual ethyl acetate, ethanol, methanol, and dichloromethane against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Ion Impurity | Ion Chromatography | Separation and conductivity detection of Cl- anions using anion-exchange column and suppressed conductivity detection. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using sodium D-line light source in a temperature-controlled polarimeter to confirm chiral integrity. |
| Residue on Ignition | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of non-volatile inorganic residue to assess inorganic ash content. |
| pH of Solution | Potentiometric pH Measurement | Measurement of aqueous solution pH (1% w/v) using calibrated glass electrode and pH meter per USP <791>. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-state phase transition temperature range using calibrated digital melting point instrument per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution using laser diffraction principle and Mie scattering theory. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and absence testing for specified pathogens per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168°C - 172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Optical Rotation | +12.0° to +14.0° (c=1, 6M HCl) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.