China Factory Direct
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| CAS number | 23256-42-0 |
| Product name | Trimethoprim lactate salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antibiotic drugs, used in the synthesis of sulfonamide antimicrobial agents | Prepared via esterification of lactic acid with trimethoprim, using catalysts such as concentrated sulfuric acid or p-toluenesulfonic acid |
| Biotechnology | Modification and conjugation of bioactive molecules to enhance drug stability | Acylation transfer reaction to introduce lactyl-trimethoprim onto side chains of peptides or proteins |
| Chemical Research | Organic synthesis reagent for constructing nitrogen-containing heterocyclic structures | Nucleophilic substitution or condensation reactions under mild conditions, suitable for small-scale laboratory synthesis |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Utilizes characteristic absorption peaks of trimethoprim lactate at specific wavelengths (e.g., 270 nm, near 230 nm) for qualitative identification. |
| Infrared Spectroscopy (IR) | Determines the infrared absorption spectrum of the sample and compares it with a reference spectrum to confirm molecular structural characteristics. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Uses a C18 column with methanol-water or buffer as mobile phase, and UV detection (around 270 nm) to quantitatively determine the main component. Offers high accuracy and strong specificity. |
| Ultraviolet Spectrophotometry (UV) | Measures absorbance at the maximum absorption wavelength and calculates content based on a standard curve. Suitable for rapid determination but has lower specificity. | |
| Related Substances (Impurity Testing) | High-Performance Liquid Chromatography (HPLC) | Separates the main peak from impurity peaks using gradient or isocratic elution, detecting degradation products or synthetic intermediates to assess purity. |
| Solution Clarity and Color | Visual Color Comparison Method / Spectrophotometry | After dissolving the sample, observe whether the solution is clear; alternatively, measure absorbance at a specific wavelength to detect the presence of colored impurities. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dries the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, measuring the percentage loss in weight to reflect moisture and volatile components. |
| Residue on Ignition | Residue on Ignition Test Method | Heats the sample at high temperature and weighs the residue to determine the content of inorganic impurities. |
| pH Value | pH Meter Determination | Dissolves trimethoprim lactate in water to a defined concentration and measures the acidity or alkalinity using a calibrated pH meter. |
| Microbial Limits | Microbial Limit Test Method | Performs tests according to pharmacopeial requirements, including total counts of aerobic bacteria, mold, and yeast, as well as testing for control organisms (e.g., Escherichia coli). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168°C - 172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.