5-Fluorocytidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2341-22-2 |
| Product name | 5-Fluorocytidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Fluorocytidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Fluorocytidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Fluorocytidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antiviral drug intermediate for synthesizing antiviral nucleoside analogs (e.g., sofosbuvir) | Used as a key starting material or intermediate in multi-step organic synthesis, including glycosylation, protection/deprotection, and coupling reactions |
| Pharmaceuticals | Anticancer research compound | Applied in laboratory-scale development of novel anticancer nucleoside derivatives to inhibit tumor cell proliferation by interfering with DNA/RNA synthesis |
| Biotechnology | Precursor for molecular probes and labeling agents | Chemically modified to synthesize fluorescent or radio-labeled nucleotides for nucleic acid hybridization, sequencing, or imaging studies |
| Research | Tool for studying nucleic acid metabolism mechanisms | Used in vitro or in cellular models to investigate pyrimidine nucleoside metabolic pathways and resistance mechanisms |
Manufacturing Quality Control of 5-Fluorocytidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~260 nm, based on peak area comparison against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., 5-fluorouracil, cytidine derivatives) using gradient HPLC with diode-array detection and relative response factor correction. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, DMF) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic elements (Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration using iodine generated in situ to determine trace water content based on stoichiometric reaction with Karl Fischer reagent. |
| Optical Rotation | Polarimetry | Measurement of specific optical rotation at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic residue after controlled high-temperature ashing (700–800 °C) followed by precise weighing of the ignited residue. |
| Microbial Contamination | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) using membrane filtration and selective agar media incubation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution (D10, D50, D90) by measuring angular scattering intensity of laser light passed through dispersed sample. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% (w/v) aqueous solution using calibrated glass electrode and pH meter under controlled temperature (25 °C). |
Technical Specifications of 5-Fluorocytidine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 210~215 °C |
| Optical Rotation | +54.0 to +58.0 deg (c=1, in water) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Fluorocytidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Fluorocytidine
Packaging of 5-Fluorocytidine
Industrial 5-Fluorocytidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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