(2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23627-61-4 |
| Product name | (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for antidepressants and anxiolytics | Reacted with hydrochloric acid via chiral synthesis to yield the hydrochloride salt |
| Chemical Synthesis | Chiral catalyst or chiral auxiliary | Used as a chiral source in asymmetric synthesis to construct chiral compounds |
| Fine Chemicals | Precursor for synthesizing other chiral compounds | Further modified through substitution reactions or functional group transformations |
Manufacturing Quality Control of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
| Test Item | Common Testing Method | Method Summary |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | The sample and reference standard are scanned under identical conditions, comparing characteristic absorption peaks to confirm molecular structure consistency. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Analyze chemical shifts, coupling constants, and integration areas in hydrogen and carbon spectra to confirm stereochemical structure and purity. | |
| Assay (Content Determination) | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase column (e.g., C18) with a UV detector; quantify the main component using external or internal standard methods. |
| Non-Aqueous Titration | In a non-aqueous solvent (e.g., glacial acetic acid), titrate basic nitrogen in hydrochloride salts with perchloric acid standard solution to calculate drug content. | |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column to separate enantiomers and determine the ratio of (R) and (S) isomers to assess optical purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate and detect possible synthetic intermediates, degradation products, and other organic impurities via gradient or isocratic elution. |
| Water Content | Karl Fischer Titration | Quantitatively determine water content using electrochemical reaction; suitable for hygroscopic hydrochloride salts. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, detect volatile organic solvents used during production (e.g., methanol, ethanol, acetone). |
| Crystalline Form Analysis | X-ray Powder Diffraction (XRPD) | Analyze characteristic diffraction peaks of the crystalline structure to identify different polymorphic forms and ensure batch consistency. |
| Melting Point | Melting Point Determination | Determine the melting temperature range using a melting point apparatus as a physical property identification and purity reference. |
| Solution Clarity and Color | Visual Color Comparison or UV-Visible Spectrophotometry | Dissolve the sample in the specified solvent and observe whether the solution is clear and colorless or compare it with standard color solutions. |
| Chloride Ion Check (Cl⁻) | Ion Chromatography or Argentometric Method | Detect free or excess chloride ions in hydrochloride salts to verify salt completeness and impurity control. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Thioacetamide Method | Detect harmful elemental residues such as lead, cadmium, and mercury to meet pharmacopoeia or ICH Q3D elemental impurity limits. |
| Particle Size Distribution | Laser Diffraction Particle Size Analysis | Determine the particle size distribution of solid particles, which affects solubility and formulation performance (especially for active pharmaceutical ingredients used in solid dosage forms). |
Technical Specifications of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Optical Rotation | -20.0° to -24.0° (c=1, in 1M HCl) |
| Melting Point | 215°C to 220°C (decomposes) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
Safety Information of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride
Industrial (2R)-2-(Diphenylmethyl)pyrrolidine Hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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