3-Oxocyclobutanecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23761-23-1 |
| Product name | 3-Oxocyclobutanecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Oxocyclobutanecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Oxocyclobutanecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Oxocyclobutanecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for synthesizing novel β-lactam antibiotics (e.g., carbapenem derivatives) | Chiral center constructed via asymmetric hydrogenation or enzymatic reduction, followed by β-lactam ring introduction via acid chloride formation/coupling |
| Pharmaceuticals | Cyclobutyl structural unit in anticancer drug candidates | Converted to 3-substituted cyclobutylamines or aryl derivatives via Suzuki or Negishi coupling |
| Materials Science | Rigid cyclobutane structure incorporator for high-performance polyimide monomers | Integrated into thermally stable polymers containing a cyclobutane backbone via high-temperature condensation polymerization with dianhydrides or diamines |
Manufacturing Quality Control of 3-Oxocyclobutanecarboxylic acid
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification (Identity) | Fourier Transform Infrared Spectroscopy (FT-IR) | Measures the infrared absorption spectrum of the sample and compares it with a reference spectrum to confirm the presence of characteristic functional groups of 3-oxocyclobutanecarboxylic acid (e.g., carbonyl C=O, carboxyl O–H). |
| Identification (Identity) | Proton Nuclear Magnetic Resonance (¹H NMR) | Utilizes nuclear magnetic resonance technology to analyze chemical shifts, coupling constants, and integration areas of hydrogen atoms, verifying structural features of the target compound and confirming its chemical structure. |
| Content Determination (Assay) | High-Performance Liquid Chromatography (HPLC) | Uses reversed-phase HPLC with a C18 column for separation and UV detection (typically at 210–230 nm) to quantitatively determine the main component content; purity is calculated using external standard or internal standard methods. |
| Related Substances / Impurity Testing | High-Performance Liquid Chromatography (HPLC) | Conducted under the same or optimized conditions as content determination, detecting and quantifying potential process impurities, degradation products, etc.; individual impurity limits are set to ensure product purity meets requirements. |
| Residual Solvents | Gas Chromatography (GC) | Employs headspace or direct injection GC with FID detection; follows pharmacopoeial or ICH guidelines to detect organic solvents (e.g., dichloromethane, ethanol, toluene) that may remain from synthesis. |
| Water Content | Karl Fischer Titration | Quantitatively determines moisture content by reacting water in the sample with Karl Fischer reagent using coulometric or volumetric methods, controlling product dryness and stability. |
| Melting Point | Capillary Melting Point Method | Sample is loaded into a capillary tube and heated at a controlled rate; the initial melting to complete melting temperature range is observed, serving as a physical constant for auxiliary identification and purity assessment. |
| pH Value (if in aqueous solution) | pH Meter Method | A solution of specified concentration is prepared, and pH is measured using a calibrated pH meter, reflecting the acid dissociation characteristics of the carboxylic acid and possible influence from impurities. |
Technical Specifications of 3-Oxocyclobutanecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 125-129 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Oxocyclobutanecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Oxocyclobutanecarboxylic acid
Safety Information of 3-Oxocyclobutanecarboxylic acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-Oxocyclobutanecarboxylic acid
Industrial 3-Oxocyclobutanecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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