4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23779-97-7 |
| Product name | 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for antimalarial drug synthesis | Used as a quinoline derivative to construct biologically active molecular scaffolds; employed in multistep organic synthesis |
| Agrochemicals | Intermediate for insecticides or fungicides | Applied in the synthesis of fluorinated heterocyclic agrochemicals; active functional groups are introduced via nucleophilic substitution or coupling reactions |
| Organic Synthesis | Organic synthesis intermediate | Utilized to prepare functionalized quinoline derivatives; participates in transition metal-catalyzed reactions such as Suzuki and Heck couplings |
Manufacturing Quality Control of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents | GC-FID | Separation and quantification of volatile organic solvents (e.g., dichloromethane, toluene) using capillary GC with flame ionization detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification via inductively coupled plasma mass spectrometry after acid digestion and dilution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water by iodine generation and stoichiometric reaction with water in anhydrous methanol-based electrolyte. |
| Chloride Impurity (inorganic Cl⁻) | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Related Substances (Impurity Profile) | HPLC-UV/DAD | Identification and quantification of structurally related impurities (e.g., des-chloro, hydrolysis, dimeric by-products) using gradient HPLC with diode-array detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating of crystalline sample; endpoint corresponds to solid-to-liquid phase change. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Determination of non-volatile inorganic residue after high-temperature incineration (~750 °C) followed by sulfuric acid treatment and weighing. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie scattering theory to derive volume-based particle size distribution. |
| Organic Volatile Impurities (e.g., triethylamine, DMF) | GC-MS | Targeted and untargeted screening/quantification of residual process amines or amides using gas chromatography coupled to mass spectrometry. |
| Optical Rotation | [α]D (Polarimetry) | Measurement of specific rotation at 589 nm using sodium D-line light to assess chiral purity (if applicable; compound is achiral, but method included for batch consistency verification per ICH Q5A). |
Technical Specifications of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 128-132°C |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
Safety Information of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE
Industrial 4-CHLORO-8-(TRIFLUOROMETHYL)QUINOLINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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