Thioflavine T Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2390-54-7 |
| Product name | Thioflavine T |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Thioflavine T
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Thioflavine T Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Thioflavine T
| Industry | Application | Process |
|---|---|---|
| Biomedical | Fluorescent stain for detection of amyloid deposits | Staining of tissue sections, followed by fluorescence microscopy to visualize amyloid fibril formation |
| Biomedical | Biomarker detection in neurodegenerative disease research | Co-incubation with brain tissue or bodily fluid samples; fluorescence signal generation upon binding to β-sheet structures |
| Biotechnology | Fluorescent nucleic acid staining enhancer | Weak binding to DNA/RNA in specific buffer systems to enhance fluorescence signal for gel electrophoresis analysis |
| Environmental Monitoring | Tracer for amyloid-like substance contamination | Fluorescent labeling and quantitative detection of abnormal protein aggregates in water or biological samples |
| Pharmaceutical R&D | Probe for high-throughput screening of amyloid aggregation inhibitors | Use as a fluorescent reporter molecule in in vitro assays to monitor compound-mediated inhibition of protein aggregation |
Manufacturing Quality Control of Thioflavine T
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | UV-Vis Spectrophotometry | Quantifies thioflavin T concentration based on absorbance at characteristic wavelength (e.g., ~412 nm) using molar absorptivity and Beer-Lambert law. |
| Loss on Drying | Gravimetric (Thermogravimetric) | Measures mass loss after drying at specified temperature (e.g., 105 C) to determine volatile content including moisture and solvents. |
| Residue on Ignition | Gravimetric (Sulfated Ash) | Determines inorganic impurities by igniting sample at high temperature (e.g., 600–700 C) and weighing residual ash after sulfuric acid treatment. |
| Heavy Metals (as Pb) | AAS or ICP-OES | Quantifies total heavy metal content by atomic absorption or optical emission spectroscopy after acid digestion and calibration against lead standard. |
| Chloride Impurity | Potentiometric Titration | Measures chloride ions via titration with silver nitrate using silver indicator electrode; endpoint detected by potential change. |
| Sulfate Impurity | Gravimetric (Barium Sulfate Precipitation) | Precipitates sulfate as BaSO4, filters, dries, and weighs to calculate sulfate content based on stoichiometric equivalence. |
| pH of Aqueous Solution | Potentiometric (pH Meter) | Measures hydrogen ion activity in a standardized aqueous solution (e.g., 1% w/v) using calibrated glass electrode system. |
| Organic Volatile Impurities | GC-FID | Separates and quantifies residual solvents (e.g., ethanol, acetone) using gas chromatography with flame ionization detection. |
| Related Substances (Impurities) | HPLC-UV | Separates and detects structurally related compounds using reversed-phase HPLC with UV detection at appropriate wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating purity and identity via thermal behavior. |
| Water Content | Karl Fischer Titration | Quantifies water via coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral molecules in solution to confirm identity and enantiomeric purity (if applicable). |
Technical Specifications of Thioflavine T
| Test Item | Specification |
|---|---|
| Appearance | Yellow Solid |
| Strength | 100±5% |
| ABS (10ppm absorbance) | 0.73-0.8 |
| pH | 1.5-3.0 |
| Loss on drying at 110℃ | ≤14% |
| Insolubles | ≤0.5% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Thioflavine T
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Thioflavine T
Packaging of Thioflavine T
Industrial Thioflavine T Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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