2,4-Dihydroxypyrimidine-5-carboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 23945-44-0 |
| Product name | 2,4-Dihydroxypyrimidine-5-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Dihydroxypyrimidine-5-carboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Dihydroxypyrimidine-5-carboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Intermediate in the synthesis of antiviral drugs (e.g., certain nucleoside analogs) | Organic synthesis for constructing pyrimidine ring structures or modifying nucleoside scaffolds |
| Biochemical Research | Substrate or inhibitor probe in enzymology studies | Enzyme activity assays and metabolic pathway analysis |
| Analytical Chemistry | Reference standard or calibration material in chromatographic or mass spectrometric analysis | Qualitative and quantitative calibration in HPLC, LC-MS, and related analytical methods |
Manufacturing Quality Control of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Using a reverse-phase C18 chromatographic column, with methanol-water or phosphate/ACN buffer systems as mobile phases, and UV detector (usually at 254 nm) for detection. It can effectively separate uracil-5-carboxylic acid from its related impurities, offering accurate quantification and is considered the gold standard for purity determination. |
| Content Determination | UV-Visible Spectrophotometry (UV-Vis) | Utilizes the characteristic absorption peaks of uracil-5-carboxylic acid at specific wavelengths (e.g., 240–260 nm). Content is calculated using a standard curve method. The method is simple, fast, and suitable for preliminary screening and routine quality control. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | ¹H NMR and ¹³C NMR provide detailed molecular structural information, confirming the chemical structure and substitution positions of uracil-5-carboxylic acid. It is commonly used for structural confirmation in new batches or during the R&D phase. |
| Molecular Weight Identification | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines HPLC separation with mass spectrometry detection to accurately determine molecular weight ([M+H]⁺ or [M−H]⁻), and identify trace impurities or degradation products. High sensitivity makes it suitable for trace analysis and impurity profiling. |
| Impurity Detection | HPLC-MS/MS or HPLC-DAD | Using tandem mass spectrometry or diode array detectors, enables simultaneous quantitative analysis of the main component and qualitative/quantitative analysis of various known/unknown impurities, meeting ICH Q3A/B requirements for impurities. |
| Residual Solvent Detection | Gas Chromatography (GC) | Uses headspace or direct injection to detect residual organic solvents (e.g., ethanol, acetone, toluene) from the synthesis process, complying with pharmacopoeia requirements (e.g., USP <467>). |
| Moisture Content Determination | Karl Fischer Titration | Specifically used to determine moisture content in the sample. Results are accurate and suitable for hygroscopic APIs, ensuring product stability. |
Technical Specifications of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 245–249 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Dihydroxypyrimidine-5-carboxylic acid
Safety Information of 2,4-Dihydroxypyrimidine-5-carboxylic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,4-Dihydroxypyrimidine-5-carboxylic acid
Industrial 2,4-Dihydroxypyrimidine-5-carboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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