China Factory Direct
|
|
| CAS number | 23995-88-2 |
| Product name | 1-(1-Methyl-4-piperidinyl)piperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for central nervous system (CNS) drugs, used in the synthesis of antipsychotics (e.g., aripiprazole analogues) and 5-HT1A receptor modulators | Serves as a key structural unit in multistep coupling reactions (e.g., Suzuki coupling, amidation, or N-alkylation), followed by purification prior to salt formation and formulation |
| Pharmaceuticals | Building block for JAK2 inhibitors and other kinase-targeted drug candidates | Introduces aromatic heterocyclic side chains via N-substitution on the piperazine ring, followed by catalytic hydrogenation or oxidation to complete molecular assembly |
| Chemicals | Precursor for novel functional materials, used in the preparation of ionic liquids or organic semiconductor dopants | Undergoes quaternization with alkyl/aryl halides under basic conditions to generate nitrogen-containing cationic structures with tunable polarity |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by gradient HPLC separation and UV response relative to main peak. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., methanol, acetone) using capillary GC with flame ionization detection. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration using iodine-sulfur dioxide reaction in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As, etc.) after acid digestion by measuring elemental mass-to-charge ratios. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing and weighing of the cooled crucible. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light through a solution in specified solvent and path length. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid under controlled heating rate. |
| pH (1% aqueous solution) | pH Meter | Determines hydrogen ion activity in aqueous solution using calibrated glass electrode system. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65-70°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.