2-(3-HYDROXYPROPYL)BENZIMIDAZOLE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2403-66-9 |
| Product name | 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Structural modification intermediate for synthesizing antiparasitic drugs (e.g., albendazole derivatives) | O-alkylation with alkyl halides under basic conditions, or esterification with acyl chlorides to construct prodrug structures |
| Organic Synthesis | Ligand scaffold for designing metal complex catalysts | Coordination with transition metal salts (e.g., Cu(II), Ni(II)) via reflux in ethanol/DMF to form N,N-bidentate chelates |
| Materials Science | Functionalized precursor for fluorescent probe molecules, enabling introduction of recognition groups | Attachment of aromatic aldehyde or boronic acid units to the hydroxyl group via Mitsunobu reaction or activated ester coupling to construct ratiometric pH- or metal ion-responsive probes |
Manufacturing Quality Control of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction with pyridine/methanol buffer system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection with high sensitivity and low detection limits. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 700-800 C followed by weighing of inorganic residue after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral centers in solution, reported as degrees per dm/g. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Electrode-based measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) at 25 C. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity patterns to calculate volume-based particle size distribution in dry or wet dispersion mode. |
| Microbial Limits | Membrane Filtration | Quantitative estimation of aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) using selective agar media and incubation per USP <61> and <62>. |
Technical Specifications of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5%(HPLC) |
| Melting Point | 142–146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
Safety Information of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE
Industrial 2-(3-HYDROXYPROPYL)BENZIMIDAZOLE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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