5-Chloro-2-thiophenecarboxylic Acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 24065-33-6 |
| Product name | 5-Chloro-2-thiophenecarboxylic Acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Chloro-2-thiophenecarboxylic Acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloro-2-thiophenecarboxylic Acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloro-2-thiophenecarboxylic Acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of drug intermediates | Used in the synthesis of thiophene-based anti-inflammatory and antimicrobial agents |
| Pesticide Industry | Preparation of insecticidal or fungicidal intermediates | Functional group introduction via substitution reactions |
| Materials Chemistry | Preparation of functional polymer monomers | Participation in condensation or free-radical polymerization reactions |
| Dye Industry | Synthesis of thiophene-containing dyes or pigments | Acting as a coupling component in azo dye synthesis |
| Organic Synthesis Research | Laboratory reagent and synthetic building block | Employed in multi-step reactions for constructing complex thiophene derivatives |
Manufacturing Quality Control of 5-Chloro-2-thiophenecarboxylic Acid
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) Proton Nuclear Magnetic Resonance (¹H NMR) Mass Spectrometry (MS) |
Confirm the structure of 2-chlorothiophene-5-carboxylic acid by characteristic absorption peaks in IR, chemical shifts and coupling constants in ¹H NMR, and molecular ion peak and fragment ions in MS. |
| Assay | High-Performance Liquid Chromatography (HPLC) Acid-Base Titration |
HPLC: Use a reverse-phase C18 column with phosphate buffer-organic solvent (e.g., methanol or acetonitrile) as mobile phase, and UV detection (typically at 220–260 nm) to quantitatively determine the main component. Acid-Base Titration: Utilize the acidity of the carboxyl group, titrate with standardized NaOH solution, and calculate the content. |
| Related Substances / Impurity Check | High-Performance Liquid Chromatography (HPLC) | Separate and detect possible process impurities (e.g., unreacted raw materials, intermediates) and degradation products (e.g., decarboxylation products, oxidation products) using gradient or isocratic elution HPLC. Determine limits using area normalization or the standard addition method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., dichloromethane, toluene, ethanol) during synthesis according to ICH Q3C guidelines, using headspace or direct injection GC-FID method. Quantify using external standard or internal standard methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight to measure the percentage of mass loss due to water or other volatile components. |
| Sulfated Ash | High-Temperature Incineration | Char the sample and then incinerate it at 700–800°C, add sulfuric acid, and weigh the residual inorganic matter to control the total amount of inorganic impurities. |
| Water Content | Karl Fischer Titration | Use volumetric or coulometric Karl Fischer titration to accurately determine the trace water content in the sample, suitable for quality control of moisture-sensitive active pharmaceutical ingredients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) Inductively Coupled Plasma Mass Spectrometry (ICP-MS) |
Determine the presence of harmful elements such as lead, cadmium, mercury, and arsenic using AAS or more sensitive ICP-MS, in accordance with pharmacopoeia or ICH Q3D guidelines for elemental impurity control. |
Technical Specifications of 5-Chloro-2-thiophenecarboxylic Acid
| Test Item | Specification |
|---|---|
| Appearance | White to gray to brown crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Chloro-2-thiophenecarboxylic Acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Chloro-2-thiophenecarboxylic Acid
Safety Information of 5-Chloro-2-thiophenecarboxylic Acid
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 5-Chloro-2-thiophenecarboxylic Acid
Industrial 5-Chloro-2-thiophenecarboxylic Acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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