Isoconazole nitrate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 24168-96-5 |
| Product name | Isoconazole nitrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Isoconazole nitrate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Isoconazole nitrate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Isoconazole nitrate
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Antifungal agent for treating dermatophytoses (e.g., tinea pedis, tinea cruris, tinea versicolor) | Applied topically (e.g., creams, gels, sprays) to infected sites to inhibit fungal cell membrane synthesis |
| Pharmaceuticals | Antifungal active pharmaceutical ingredient (API) in combination formulations to enhance efficacy | Formulated with other antifungal or anti-inflammatory agents into topical combination products |
| Chemical Research | Experimental compound for studying fungal metabolic pathways | Evaluated for antifungal activity in in vitro fungal culture models |
| Biotechnology | Fungal target screening and mechanistic drug research | Assessed via enzyme inhibition assays or gene expression analysis for effects on enzymes involved in fungal cell wall/membrane synthesis |
Manufacturing Quality Control of Isoconazole nitrate
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of econazole nitrate and compare it with the standard reference spectrum to confirm its chemical structural characteristics. |
| High-Performance Liquid Chromatography (HPLC) | Perform qualitative identification based on retention time matching with that of the reference substance. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a mobile phase consisting of methanol-water or acetonitrile-buffer salt system, detected by UV detector (typically 220–260 nm), and calculate the main component content using external standard method. |
| Related Substances (Impurity) Testing | High-Performance Liquid Chromatography (HPLC) | Employ gradient or isocratic elution procedures to separate and quantify potential organic impurities (e.g., degradation products, synthetic intermediates). Typically use area normalization method or the main component self-control method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detection. Control residual solvents such as methanol, acetone, dichloromethane within limits specified in pharmacopoeia. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying at Atmospheric Pressure | Dry the sample to constant weight at a specified temperature (e.g., 105°C) and determine the percentage of mass loss due to moisture or other volatile components. |
| Residue on Ignition | High-Temperature Incineration Method | Char the sample, then ignite it at 700–800°C in a high-temperature furnace. Weigh the remaining inorganic residue to assess the level of inorganic impurities. |
| pH Value | pH Meter Measurement | Dissolve the sample in water to a specified concentration (e.g., 1%), measure pH using a calibrated pH meter. Econazole nitrate typically exhibits weak acidity due to the presence of nitrate groups. |
| Dissolution (for formulations) | Dissolution Testing (Paddle Method or Basket Method) | Simulate physiological conditions (e.g., pH 1.2 or 6.8 medium), measure drug release over time using HPLC or UV spectrophotometry, and evaluate the release performance of the formulation. |
Technical Specifications of Isoconazole nitrate
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Isoconazole nitrate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Isoconazole nitrate
Packaging of Isoconazole nitrate
Industrial Isoconazole nitrate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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