2,2',6,6'-Tetramethyl-4,4'-biphenol Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2417-04-1 |
| Product name | 2,2',6,6'-Tetramethyl-4,4'-biphenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,2',6,6'-Tetramethyl-4,4'-biphenol
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,2',6,6'-Tetramethyl-4,4'-biphenol Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,2',6,6'-Tetramethyl-4,4'-biphenol
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing thyroid hormone drugs (e.g., levothyroxine sodium) | Condensed with sodium chloroacetate under alkaline conditions, followed by cyclization and purification to produce levothyroxine sodium |
| Organic Synthesis | Used as a monomer for liquid crystal materials or as a structural unit in functional polymers | Incorporated into liquid crystal molecular frameworks via oxidative coupling or palladium-catalyzed cross-coupling reactions, or copolymerized in polyesters/polycarbonates |
| Analytical Chemistry | Used as a reference standard or derivatization reagent in HPLC-based thyroid hormone assays | Methylated or silylated prior to quantitative analysis of thyroxine (T4) and its metabolites in serum by HPLC-UV or LC-MS |
Manufacturing Quality Control of 2,2',6,6'-Tetramethyl-4,4'-biphenol
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 280 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using HPLC coupled with diode array detection; peak purity and threshold evaluation per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, toluene, DMF) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, per USP <233> and ICH Q3D. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Ignition at 700-800 C followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light and against standard references. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie theory to calculate size distribution profile. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume before and after standardized tapping cycles per USP <616>. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measured upon heating to 105 C for 2 hours, indicating volatile and moisture content. |
Technical Specifications of 2,2',6,6'-Tetramethyl-4,4'-biphenol
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 245–249 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,2',6,6'-Tetramethyl-4,4'-biphenol
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,2',6,6'-Tetramethyl-4,4'-biphenol
Safety Information of 2,2',6,6'-Tetramethyl-4,4'-biphenol
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,2',6,6'-Tetramethyl-4,4'-biphenol
Industrial 2,2',6,6'-Tetramethyl-4,4'-biphenol Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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