China Factory Direct
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| CAS number | 24250-85-9 |
| Product name | L-4-Iodophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Precursor for radiolabeled tracers used in positron emission tomography (PET) imaging probe development | Radiolabeling with iodine-124 or iodine-131 via electrophilic substitution or metal-catalyzed coupling reactions |
| Biochemical Research | Iodinated non-canonical amino acid for site-specific protein modification, structure–function studies, and photo-crosslinking experiments | Incorporated into peptide chains during solid-phase peptide synthesis (SPPS) using Fmoc protection strategy |
| Medicinal Chemistry | Intermediate for targeted therapeutic agents, including tyrosine kinase inhibitors and receptor antagonists | Construction of fused aromatic ring systems via palladium-catalyzed cross-coupling (e.g., Heck, Suzuki reactions), or preparation of derivatives via reductive amination |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 254 nm using a calibrated standard curve. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with UV detection and peak area ratio calculation. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature and vacuum until constant weight is achieved. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other heavy metals after acid digestion and plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Turbidimetry | Formation of barium sulfate precipitate in acidic medium; quantification via light scattering measurement. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration based on the stoichiometric reaction of iodine with water in pyridine/methanol medium. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light at 589 nm, corrected for concentration and path length to calculate [alpha]D. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens following compendial microbiological methods. |
| Test Item | Specification |
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| Appearance | Off-white powder |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 245-249°C |
| Optical Rotation | +19.0 to +23.0° (c=1, 1M HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.