1-cyclohexylpiperazine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 245487-40-5 |
| Product name | 1-cyclohexylpiperazine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-cyclohexylpiperazine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-cyclohexylpiperazine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-cyclohexylpiperazine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as an intermediate in the synthesis of antipsychotic drugs or neuromodulators | Applied in organic synthesis reactions, such as aminoalkylation and condensation |
| Chemical Research | Used to construct piperazine-containing compound libraries for screening biologically active molecules | Applied in multistep organic synthesis, commonly involving coupling or cyclization reactions |
| Medicinal Chemistry | Used as a ligand or structural building block in the design of GPCR-targeted compounds | Applied in molecular docking-assisted design, combined with solid-phase or solution-phase synthesis techniques |
Manufacturing Quality Control of 1-cyclohexylpiperazine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., 1-cyclohexylpiperazine, N-oxide, dechlorinated analogs) using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, with detection limits <1 ppb. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion-specific separation and quantification (IC) or argentometric titration with AgNO₃ endpoint detection. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | High-temperature incineration followed by sulfuric acid treatment and weighing of inorganic residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | [α]D | Polarimetric measurement at 589 nm to confirm chiral integrity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Dry or wet dispersion analysis to determine D10, D50, D90 values per ISO 13320. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens per Ph. Eur. 2.6.12. |
Technical Specifications of 1-cyclohexylpiperazine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-cyclohexylpiperazine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Packaging of 1-cyclohexylpiperazine hydrochloride
Industrial 1-cyclohexylpiperazine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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