China Factory Direct
|
|
| CAS number | 2458-12-0 |
| Product name | 3-Amino-4-methylbenzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of anti-inflammatory agents, local anesthetics, and other active pharmaceutical ingredients (APIs) | Introduced into target molecular structures via acylation, esterification, or coupling reactions |
| Dyes and Pigments | Used as an intermediate for azo dyes and functional dyes | Participates in diazotization-coupling reactions to construct chromophore structures |
| Agricultural Chemicals | Used as an intermediate in the synthesis of certain herbicides or plant growth regulators | Active molecular frameworks are constructed through organic synthesis steps such as substitution and condensation |
| Polymer Materials | Used as a functional monomer or modifier in specialty polymer synthesis | Carboxyl or amino groups participate in polymerization or grafting reactions to impart specific material properties |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with a mobile phase of phosphate buffer and organic solvent, and a UV detector (e.g., 254 nm) to quantify the main component's purity. Suitable for accurate determination of the target compound content and related substances. |
| Related Substances | HPLC (Gradient Elution) | Employs a gradient elution program to separate potential process impurities or degradation products. Impurity levels are evaluated by comparing retention times and peak areas with reference standards. Complies with pharmacopoeial or ICH Q3A/B requirements. |
| Loss on Drying | Drying to Constant Weight (105°C) | Sample is dried in an oven at 105°C until constant weight is achieved. The percentage weight loss is calculated to control moisture and volatile content. |
| Sulfated Ash / Residue on Ignition | High-Temperature Ashing in Muffle Furnace | Sample is ignited at 700–800°C in a muffle furnace until constant weight. The residual inorganic material is weighed to assess levels of inorganic impurities or metal catalyst residues. |
| Heavy Metals | Thioacetamide Method or ICP-MS | Chinese Pharmacopoeia thioacetamide colorimetric method: reacts with thioacetamide under weakly acidic conditions to produce color, compared with a standard lead solution; or use ICP-MS for precise quantification of multiple heavy metal elements. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Uses headspace sampling to vaporize volatile organic solvents, which are then separated on a capillary column and detected by FID or MS. Suitable for analyzing common residual solvents such as methanol, ethanol, and ethyl acetate. |
| Melting Point | Capillary Melting Point Apparatus | Determines the initial and final melting temperatures using a digital melting point apparatus according to pharmacopoeial methods. Used to assess crystalline purity and conformance to standard ranges (literature value approximately 160–165°C). |
| pH (Solution) | pH Meter Method | Prepare an aqueous solution of defined concentration (e.g., 1%), and measure directly using a calibrated pH meter to evaluate acidity/basicity and stability. |
| Structural Confirmation | Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | IR confirms characteristic functional group absorption peaks; ¹H/¹³C NMR provides information on hydrogen and carbon environments; MS determines molecular weight and fragment structures. Combined, these techniques confirm chemical structure identity. |
| Water Content | Karl Fischer Titration | Uses volumetric or coulometric Karl Fischer reagent to titrate trace water in the sample. Suitable for quality control of moisture-sensitive active pharmaceutical ingredients. |
| Test Item | Specification |
|---|---|
| Appearance | White to gray to brown crystalline powder |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.