L-Leucine benzyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2462-35-3 |
| Product name | L-Leucine benzyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for L-Leucine benzyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk L-Leucine benzyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of L-Leucine benzyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Peptide Drug Synthesis | Serves as an amino acid raw material; the carboxyl group is protected with a benzyl ester, enabling participation in solid-phase or solution-phase peptide synthesis (e.g., thymopentin, octreotide), followed by deprotection. |
| Pharmaceutical Industry | Chiral Drug Intermediate | Acts as a chiral building block for synthesizing L-leucine-containing active pharmaceutical ingredients (APIs) used in anticancer and immunomodulatory drugs. |
| Biochemistry | C-Terminal Modification of Peptide Chains | Used in biochemical synthesis research to cap the C-terminus of peptide chains, facilitating structural and functional studies of proteins and peptides. |
| Organic Synthesis | Chiral Catalyst Support | Serves as a chiral precursor for synthesizing chiral catalysts or ligands applied in asymmetric hydrogenation or oxidation reactions. |
| Chemical R&D | Protected Amino Acid Research | Employed in fundamental research on novel deprotection strategies or solid-phase synthesis resin linkage technologies. |
Manufacturing Quality Control of L-Leucine benzyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 205 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, toluene, DMF). |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine trace water content in the sample. |
| Heavy Metals | ICP-OES | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma excitation. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 degC and sodium D-line (589 nm) to confirm chiral integrity. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after high-temperature ashing at 700-800 degC. |
| pH of Solution | pH Meter | Measurement of aqueous solution pH (1% w/v) using calibrated glass electrode system. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size by measuring angular scattering pattern of laser light. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens per pharmacopeial methods. |
| Appearance | Visual Inspection | Assessment of physical form, color, and clarity of solid or solution under controlled lighting conditions. |
Technical Specifications of L-Leucine benzyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148-152°C |
| Optical Rotation | -15.0° to -17.0° (c=1, 6N HCl) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of L-Leucine benzyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of L-Leucine benzyl ester hydrochloride
Safety Information of L-Leucine benzyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of L-Leucine benzyl ester hydrochloride
Industrial L-Leucine benzyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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