1-N-Boc-cis-1,4-cyclohexyldiamine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 247570-24-7 |
| Product name | 1-N-Boc-cis-1,4-cyclohexyldiamine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-N-Boc-cis-1,4-cyclohexyldiamine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-N-Boc-cis-1,4-cyclohexyldiamine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-N-Boc-cis-1,4-cyclohexyldiamine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral ligand precursor; building block for drug molecules | Used in the synthesis of targeted small-molecule drugs containing a cis-1,4-cyclohexanediamine scaffold (e.g., protein kinase inhibitors, G protein-coupled receptor modulators); the Boc group protects nitrogen atoms, enabling subsequent selective acylation, alkylation, or coupling reactions |
| Fine Chemicals | Asymmetric catalysis intermediate | Serves as a bidentate nitrogen ligand precursor in palladium- or nickel-catalyzed C–N cross-coupling reactions; after Boc deprotection, it coordinates to the metal center to construct chiral catalytic systems |
| Materials Science | Functionalized polymer monomer | After Boc deprotection, undergoes condensation polymerization with diisocyanates or dicarboxylic acids to produce heat-resistant polyamides or polyureas featuring a rigid cyclohexane structure |
Manufacturing Quality Control of 1-N-Boc-cis-1,4-cyclohexyldiamine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV; identification via retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, methanol) by headspace GC with flame ionization detection using calibrated standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration where iodine reacts stoichiometrically with water in anhydrous pyridine/methanol medium. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Quantifies trace metal impurities after acid digestion using inductively coupled plasma mass spectrometry for multi-element detection at sub-ppt levels. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using a digital polarimeter at 20 deg C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Acid Value | Acid-Base Titration | Titration with standardized KOH solution in ethanol/isopropanol to quantify free carboxylic acid or acidic degradation products. |
| Residual Boc Group Content | NMR (1H) | Quantifies intact tert-butoxycarbonyl group via integration of tert-butyl singlet (9H) at ~1.4 ppm relative to diagnostic ring protons. |
| Heavy Metals | USP <231> Sulfide Precipitation | Semi-quantitative limit test detecting Pb, As, Hg, Cd by colorimetric comparison after sulfide precipitation in acidic medium. |
| Particle Size Distribution | Laser Diffraction | Measures dry or wet dispersed particle size distribution using Mie scattering theory and optical diffraction patterns. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms per USP <61> by filtration, membrane transfer to soybean-casein digest agar, and colony enumeration after incubation. |
Technical Specifications of 1-N-Boc-cis-1,4-cyclohexyldiamine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 75–79°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in methanol) |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-N-Boc-cis-1,4-cyclohexyldiamine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-N-Boc-cis-1,4-cyclohexyldiamine
Packaging of 1-N-Boc-cis-1,4-cyclohexyldiamine
Industrial 1-N-Boc-cis-1,4-cyclohexyldiamine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply