BOC-L-Methionine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2488-15-5 |
| Product name | BOC-L-Methionine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-L-Methionine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-L-Methionine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-L-Methionine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Amino acid protecting reagent for peptide-based drug synthesis | Used as the tert-butoxycarbonyl (Boc) protected derivative of L-methionine in solid-phase peptide synthesis (SPPS) to selectively incorporate sulfur-containing amino acid residues |
| Biochemical Research | Modified amino acid precursor for protein structure and function studies | Provides controlled-release methionine units in enzymatic or chemical modification reactions, enabling isotopic labeling (e.g., ¹³C, ¹⁵N) or site-directed mutagenesis simulation |
| Diagnostics Reagent Development | Building block for radiolabeled or fluorescent probes | Conjugated to targeting peptide backbones via coupling reactions (e.g., amide bond formation, click chemistry); subsequent deprotection enables preparation of PET/SPECT imaging probes |
Manufacturing Quality Control of BOC-L-Methionine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with quantitation via UV detection to determine enantiomeric excess. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine, sulfur dioxide, and pyridine in methanol to determine water content by stoichiometric reaction. |
| Residual Solvents | GC-FID | Gas chromatographic separation followed by flame ionization detection to quantify common organic solvents (e.g., ethyl acetate, methanol) based on retention time and peak area. |
| Heavy Metals | ICP-MS | Multi-element detection of trace metals (e.g., Pb, Cd, Hg, As) by plasma ionization and mass spectrometric quantification. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using an anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate anions using an anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., Boc-Gly, methionine, des-Boc derivative) using gradient reversed-phase HPLC. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a polarimeter at 20 degrees C with sodium D-line (589 nm) light. |
| pH of Solution | Potentiometric pH Measurement | Measurement of hydrogen ion activity in aqueous solution using a calibrated glass electrode and reference electrode. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile inorganic residue remaining after controlled high-temperature incineration of the sample. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and absence testing for specified pathogens using membrane filtration followed by culture on appropriate media. |
Technical Specifications of BOC-L-Methionine
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -24.0 to -20.0 deg (c=1, in 1M HCl) |
| Melting Point | 138 to 142 °C |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-L-Methionine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-L-Methionine
Packaging of BOC-L-Methionine
Industrial BOC-L-Methionine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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