1-Methyl-1H-pyrazole-4-carbaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 25016-11-9 |
| Product name | 1-Methyl-1H-pyrazole-4-carbaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1-Methyl-1H-pyrazole-4-carbaldehyde
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-Methyl-1H-pyrazole-4-carbaldehyde Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-Methyl-1H-pyrazole-4-carbaldehyde
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate for the antidepressant vortioxetine | Serves as a key intermediate in constructing the drug’s core scaffold via reaction with thioacetic acid and amine compounds |
| Agrochemical Industry | Intermediate for fungicides | Used to synthesize the critical pyrazole ring moiety of methoxyacrylate fungicides, such as pyraclostrobin |
| Pharmaceutical Industry | Building block for drug molecules | Leverages aldehyde reactivity in reductive amination to introduce amino side chains, enabling synthesis of pyrazole derivatives with potential biological activity |
| Organic Synthesis | Synthesis of fine chemicals | Acts as an electrophile in Grignard or Wittig reactions to produce corresponding alcohol or alkene derivatives |
| Pharmaceutical Industry | Intermediate for COX-2 inhibitors | Used in synthesizing nonsteroidal anti-inflammatory drugs containing the 1-methyl-4-substituted pyrazole structure |
Manufacturing Quality Control of 1-Methyl-1H-pyrazole-4-carbaldehyde
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification and reporting of individual impurities above threshold limits. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 750 C in platinum crucible followed by weighing of residual inorganic ash after sulfuric acid treatment. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state and color under controlled white light against established reference standards. |
| Odor | Olfactory Assessment | Qualified personnel evaluation for characteristic odor and absence of off-odors indicating degradation or contamination. |
| pH of Aqueous Solution | pH Meter | Measurement of pH in a saturated aqueous suspension (1% w/v) using calibrated pH electrode. |
| Loss on Drying | Thermogravimetric Analysis | Weight loss measurement upon heating at 105 C for 2 hours, reflecting volatile content including moisture and residual solvents. |
Technical Specifications of 1-Methyl-1H-pyrazole-4-carbaldehyde
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1-Methyl-1H-pyrazole-4-carbaldehyde
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-Methyl-1H-pyrazole-4-carbaldehyde
Safety Information of 1-Methyl-1H-pyrazole-4-carbaldehyde
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 1-Methyl-1H-pyrazole-4-carbaldehyde
Industrial 1-Methyl-1H-pyrazole-4-carbaldehyde Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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