China Factory Direct
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| CAS number | 25137-01-3 |
| Product name | Ethyl (3R)-piperidine-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty GradeCosmetic GradeFood Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for certain antidepressants and psychotropic drugs | Prepared via organic synthesis methods, such as esterification or condensation reactions |
| Chemical Synthesis | Organic synthesis intermediate for constructing complex molecular frameworks | Synthesized via palladium-catalyzed coupling reactions or nucleophilic substitution reactions |
| Fine Fragrance Industry | Synthesis of fragrance compounds | Chemically modified via transesterification or reduction reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation and quantification of (R)- and (S)-enantiomers on a chiral stationary phase, calculating ee from peak area ratio. |
| Residual Solvents (Ethanol, Ethyl Acetate, etc.) | GC-FID | Headspace or direct injection GC with flame ionization detection, quantifying solvents against internal/external calibration standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, based on mass-to-charge ratio detection with high sensitivity and low detection limits. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and conductivity detection of chloride anions in aqueous extract, calibrated against chloride standard solutions. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (500–600 °C) and weighing. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective visual assessment against water or APHA color standards under controlled lighting conditions. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation in solution using a digital polarimeter at 20 °C and sodium D-line (589 nm). |
| pH (10% w/v aqueous solution) | pH Potentiometry | Electrochemical measurement using calibrated pH electrode in saturated aqueous suspension or clarified solution. |
| Related Substances (Impurity Profile) | HPLC-UV (with forced degradation) | Detection and quantification of structurally related impurities (e.g., hydrolysis, oxidation products) using gradient HPLC-UV with method validation per ICH Q2(R2). |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -2.0 to -1.0 (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.