China Factory Direct
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| CAS number | 25181-50-4 |
| Product name | (S)-3-Amino-piperidine-2,6-dione hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antiviral drugs | Prepared via organic synthesis using (S)-3-aminopiperidine-2,6-dione as the starting material, followed by hydrochlorination |
| Pharmaceuticals | Intermediate in the synthesis of antibiotics | Serves as a key intermediate in antibiotic synthesis, participating in multiple organic reaction steps |
| Chemical Research | Organic synthesis reagent | Used to construct piperidine-based structures and introduce a chiral center into target molecules |
| Pharmaceuticals | Intermediate in the synthesis of cardiovascular drugs | Serves as a critical intermediate in cardiovascular drug synthesis, involved in condensation and cyclization reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to reference standard. |
| Chiral Purity | Chiral HPLC | Resolves (R)- and (S)-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak areas. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration with iodine-based reagent, based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, acetone) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration | Determines chloride ion concentration by titration with silver nitrate using silver/silver chloride electrode. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities using gradient HPLC with UV detection. |
| pH of Aqueous Solution | pH Meter Measurement | Measures hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode pH meter. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after drying at 105 C under vacuum for 2 hours. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against established visual standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular scattering pattern of laser light passed through dispersed sample. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic microorganisms and detects specified pathogens using membrane filtration followed by incubation on selective media. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -72.0 to -66.0 deg (c=1, H2O) |
| Melting Point | 210 to 215 °C (decomposes) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.2% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.