FMOC-MENVA-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 252049-05-1 |
| Product name | FMOC-MENVA-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-MENVA-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-MENVA-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-MENVA-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for peptide drug synthesis | Introduction of N-methylated amino acid residues in solid-phase or liquid-phase peptide synthesis (SPPS/LPPS) |
| Biochemical Research | Construction of model peptide segments containing N-methyl amino acids to study conformation–bioactivity relationships | Amino group protection using the Fmoc strategy, followed by stepwise coupling reactions |
| Medicinal Chemistry | Development of novel peptide-based lead compounds with improved metabolic stability and membrane permeability | Coupling with standard Fmoc-protected amino acids, followed by iterative deprotection and condensation cycles to assemble the target peptide chain |
Manufacturing Quality Control of FMOC-MENVA-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies FMOC-N-methyl-L-norvaline by UV absorbance at 265 nm using a reversed-phase C18 column and gradient elution with aqueous buffer and acetonitrile. |
| Chiral Purity | Chiral HPLC | Resolves enantiomers using a chiral stationary phase; detects L-enantiomer excess by retention time comparison and peak area ratio. |
| Water Content | Karl Fischer Titration | Measures trace water via coulometric or volumetric titration where iodine reacts stoichiometrically with water in pyridine/methanol solvent. |
| Residual Solvents | GC-FID | Quantifies residual solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection using a polar capillary column. |
| Heavy Metals | ICP-MS | Detects trace heavy metals (Pb, Cd, Hg, As) by plasma ionization and mass spectrometric quantification with isotope dilution calibration. |
| Residual Palladium | ICP-OES | Quantifies palladium residues from coupling catalysts using inductively coupled plasma optical emission spectroscopy at characteristic wavelengths. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid content by titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint detection. |
| FMOC Group Content | UV-Vis Spectrophotometry | Measures FMOC chromophore concentration at 301 nm after base-induced cleavage, based on molar absorptivity of dibenzofulvene-piperidine adduct. |
| Related Substances | HPLC-UV | Identifies and quantifies impurities (e.g., dipeptides, deprotected species, epimers) using stability-indicating reversed-phase HPLC method. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of particulates or clumps against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated apparatus per USP <741> guidelines. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified vacuum and temperature conditions (e.g., 60 C, 2 h, 0.1 mbar). |
Technical Specifications of FMOC-MENVA-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=99.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -28.0 to -24.0 deg (c=1, in DMF) |
| Melting Point | 148 to 152 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-MENVA-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-MENVA-OH
Packaging of FMOC-MENVA-OH
Industrial FMOC-MENVA-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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