China Factory Direct
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| CAS number | 25245-34-5 |
| Product name | 1-Bromo-2,5-dimethoxybenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Used as a precursor in the synthesis of antidepressants and 5-HT2A receptor agonists (e.g., DOB analogs) | Bromination: Prepared via diazotization followed by Sandmeyer reaction of 2,5-dimethoxyaniline, or via bromination of 2,5-dimethoxyphenol |
| Organic Synthesis | Employed as an aryl bromide in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct polysubstituted aromatic ring systems | Palladium-catalyzed coupling: Undergoes C–C bond formation with arylboronic acids, alkenes, etc., catalyzed by Pd(PPh₃)₄ or Pd(dppf)Cl₂ |
| Materials Science | Applied in the synthesis of optoelectronic functional molecules (e.g., hole-transport materials for OLEDs, monomers for conjugated polymers) | Brominated aryl rings serve as coupling sites; electron-donating or electron-withdrawing units are introduced via Stille or Suzuki polymerization |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | GC-FID or GC-MS | Quantitative determination based on peak area comparison against a certified reference standard using gas chromatography with flame ionization or mass spectrometric detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration measuring water by reaction with iodine, sulfur dioxide, and base in anhydrous methanol/pyridine medium. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing and subsequent weighing. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of trace metals via atomic emission spectroscopy following acid digestion and plasma excitation. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Related Substances | HPLC-UV | Identification and quantification of structurally related impurities using reversed-phase chromatography and UV absorbance detection. |
| Acid Value | Acid-Base Titration | Determination of free acidic impurities by titration with standardized sodium hydroxide solution using phenolphthalein indicator. |
| Color (APHA) | Visual Comparison or Spectrophotometry | Assessment of yellowness/brownness by matching sample color to APHA platinum-cobalt standard solutions or measuring absorbance at 430 nm. |
| Density | Digital Density Meter | Measurement of mass per unit volume at specified temperature using oscillating U-tube principle. |
| Refractive Index | Refractometry | Determination of light bending angle at air-sample interface using calibrated refractometer at specified temperature. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.545–1.555 |
| Relative Density (20°C/25°C) | 1.32–1.34 g/cm³ |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.