3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 253168-94-4 |
| Product name | 3-Ethoxy-4-Methoxy-alpha-[(Methylsulfonyl)Methyl]-benzeneMethanaMine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 253168-94-4
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 253168-94-4 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 253168-94-4
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for apremilast synthesis; used in manufacturing PDE4 inhibitor drugs for psoriasis and psoriatic arthritis | Prepared via multi-step organic synthesis—including alkylation, sulfonylation, and reductive amination—followed by condensation and cyclization in apremilast production |
Manufacturing Quality Control of 253168-94-4
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase C18 column and calibrated standard. |
| Related Substances | HPLC-UV or HPLC-MS | Separates and detects structurally related impurities based on retention time and spectral match; MS provides confirmation. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, ethyl acetate) via flame ionization detection after headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by electrochemical titration with iodine-based reagent in anhydrous methanol medium. |
| Heavy Metals | ICP-MS | Quantifies toxic elements (e.g., Pb, Cd, Ni) at sub-ppb levels using plasma ionization and mass spectrometric detection. |
| Optical Rotation | [α]D | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by precise weighing of residual residue. |
| Sulfate Residue | Ion Chromatography (IC) | Quantifies sulfate ions released from sulfonamide/sulfonyl groups after acid hydrolysis and anion separation. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in aqueous suspension to assess acid–base character and salt formation propensity. |
Technical Specifications of 253168-94-4
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 253168-94-4
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 253168-94-4
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Industrial 253168-94-4 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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