China Factory Direct
|
|
| CAS number | 254454-54-1 |
| Product name | 1-Boc-3-iodoazetidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key organic synthesis intermediate | Used to construct the azetidine scaffold and introduce nitrogen-containing heterocyclic structural units into target drug molecules. |
| Pharmaceutical Chemicals | Drug discovery and development | Applied in the synthesis of novel small-molecule drugs, particularly for screening and developing therapeutics targeting central nervous system disorders, infectious diseases, and oncology. |
| Pharmaceutical Chemicals | Synthesis of amine derivatives | Leverages iodine atom reactivity to form C–N bonds via coupling reactions (e.g., Buchwald–Hartwig amination) or nucleophilic substitution. |
| Pharmaceutical Chemicals | Amino protecting group application | Serves as a nitrogen-protecting group (Boc) in multistep syntheses to prevent undesired side reactions, with removal under acidic conditions. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 210-230 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient HPLC-UV with suitable column and mobile phase. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine-based reagent in anhydrous methanol. |
| Heavy Metals | ICP-OES | Quantifies elements such as Pb, Cd, Hg, As, and Ni by inductively coupled plasma optical emission spectroscopy after acid digestion. |
| Residual Iodine | Ion Chromatography | Measures free iodide ions using suppressed ion chromatography with conductivity detection. |
| Acid Value | Acid-Base Titration | Determines acidic impurities by titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint. |
| Chloride Content | Potentiometric Titration | Quantifies chloride ions via argentometric titration with silver nitrate and silver-sulfide electrode detection. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid or solution against established visual standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric Analysis | Measures volatile content by weight loss after drying under specified temperature and vacuum conditions. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size distribution in dry powder form using laser scattering principle and Mie theory. |
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic odor |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.