3-Fluoro-4-bromopyridine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 2546-52-3 |
| Product name | 3-Fluoro-4-bromopyridine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Fluoro-4-bromopyridine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Fluoro-4-bromopyridine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Fluoro-4-bromopyridine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor, antiviral, and central nervous system agents | Used to construct fluorinated pyridine-based active molecular scaffolds via nucleophilic substitution, Suzuki coupling, and related reactions |
| Agrochemicals | Building block for synthesizing novel fluorinated heterocyclic insecticides or herbicides | Applied as a key synthon in heterocycle structural modification to enhance biological activity and selectivity |
| Materials Science | Preparation of organic optoelectronic functional materials (e.g., OLED emissive layer materials) | Employed in metal-catalyzed cross-coupling reactions to introduce fluorine/bromine functionalities, thereby tuning electronic properties of materials |
Manufacturing Quality Control of 3-Fluoro-4-bromopyridine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time comparison and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with iodine-based reagent to determine trace water content in solid samples. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, with detection at sub-ppb levels. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Mass loss measurement after heating sample at 700-800 C to determine inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating purity and identity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measurement of pH in a saturated aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion via laser scattering to determine D10, D50, D90 values. |
| Loss on Drying | Thermogravimetric Analysis | Mass loss measured under controlled heating (105 C, 2 h) to assess volatile content including residual moisture and solvents. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity (if applicable) and detect racemization. |
Technical Specifications of 3-Fluoro-4-bromopyridine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 124.0–127.0 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Fluoro-4-bromopyridine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Fluoro-4-bromopyridine hydrochloride
Safety Information of 3-Fluoro-4-bromopyridine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3-Fluoro-4-bromopyridine hydrochloride
Industrial 3-Fluoro-4-bromopyridine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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