China Factory Direct
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| CAS number | 25475-76-7 |
| Product name | THIOPHEN-3-AMINE HYDROCHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of drug molecules | Used to synthesize target pharmaceuticals via reaction with other compounds |
| Materials Science | Preparation of functional materials | Applied in the preparation of organic semiconductor materials with specific properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC with UV detection | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV absorbance at ~254 nm. |
| Loss on Drying (LOD) | Gravimetric thermogravimetry | Measurement of mass loss after drying under controlled temperature and vacuum to determine volatile content, including residual solvents and moisture. |
| Residual Solvents (e.g., ethanol, acetone) | Gas Chromatography (GC-FID) | Separation and quantification of volatile organic solvents using capillary GC column and flame ionization detection relative to internal standard calibration. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification via plasma ionization and mass spectrometric detection with isotopic resolution and low detection limits. |
| Chloride Impurity (Cl⁻) | Potentiometric titration with AgNO₃ | Titration using silver nitrate solution with silver/silver chloride electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| Related Substances | HPLC with diode-array detection (DAD) | Identification and quantification of structurally related impurities (e.g., 3-nitrothiophene, 3-acetamidothiophene) using gradient elution and spectral library matching. |
| pH of Aqueous Solution (1% w/v) | pH potentiometry | Measurement of hydrogen ion activity in aqueous suspension using calibrated pH electrode and standardized buffer solutions. |
| Melting Point | Capillary melting point apparatus | Determination of solid-to-liquid phase transition temperature range using controlled heating and visual observation of meniscus movement. |
| Sulfate (SO₄²⁻) | Barium sulfate gravimetric method | Precipitation of sulfate as insoluble BaSO₄ under acidic conditions, followed by filtration, drying, and weighing of the pure precipitate. |
| Water Content (Karl Fischer) | Coulometric Karl Fischer titration | Electrochemical generation of iodine to react stoichiometrically with water; quantification based on total charge required for complete reaction. |
| Specific Optical Rotation | [α]D | Measurement of plane-polarized light rotation angle using sodium D-line (589 nm) in solution, indicating chiral purity and identity confirmation. |
| Particle Size Distribution | Laser diffraction analysis | Determination of size distribution by analyzing angular variation in laser light scattering intensity from dispersed particles in liquid medium. |
| Microbial Limits | Membrane filtration followed by agar culture | Enumeration of aerobic mesophilic bacteria and fungi using selective media and incubation per pharmacopoeial guidelines (e.g., USP <61>). |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.