China Factory Direct
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| CAS number | 25487-66-5 |
| Product name | 3-Carboxyphenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Raw material or intermediate for Suzuki-Miyaura cross-coupling reactions | Used to construct biaryl frameworks for active pharmaceutical ingredient (API) synthesis |
| Pharmaceuticals | Synthesis of enzyme inhibitors or receptor antagonists | Participates in targeted drug molecule construction via specific boronic acid group binding |
| Materials | Monomer for conjugated polymer synthesis | Used to synthesize emissive materials (e.g., OLEDs) or electron-transport materials containing fluorene or carbazole units |
| Chemicals | Organic synthesis building block | Serves as a coupling reagent to form carbon–carbon bonds with aryl halides under palladium catalysis |
| Sensing | Probe for saccharide or diol molecular recognition | Enables fluorescent sensor fabrication through reversible covalent binding between boronic acid and diols |
| Test Item | Common Testing Methods | Method Overview |
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| Identification Test | Fourier Transform Infrared Spectroscopy (FT-IR) | Measure the infrared absorption spectrum of the sample and compare it with a reference spectrum to confirm characteristic functional groups of 3-carboxyphenylboronic acid (e.g., B–OH, C=O, O–H absorption peaks) for structural confirmation. |
| Proton Nuclear Magnetic Resonance Spectroscopy (¹H NMR) | Obtain the ¹H NMR spectrum of the sample in a deuterated solvent, and verify molecular structure and purity based on chemical shifts, integration areas, and coupling constants. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with an appropriate mixture of water and organic solvent (e.g., methanol or acetonitrile) as the mobile phase, and quantify the main component using a UV detector (typically at 200–260 nm wavelength), offering high sensitivity and good reproducibility. |
| Related Substances / Impurity Check | High-Performance Liquid Chromatography (HPLC) | Similar conditions to the assay, but with optimized gradient elution to separate potential impurities (e.g., unreacted starting materials, by-products, degradation products); impurity content is calculated via peak area normalization or corrected factor methods. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying | Dry the sample to constant weight at a specified temperature (e.g., 105°C) and measure the mass loss to evaluate moisture and volatile component content. |
| Residue on Ignition | High-Temperature Ashing | Carbonize the sample, then ignite at high temperature (typically 700–800°C), and weigh the residual inorganic matter to control the limit of inorganic impurities. |
| pH Value | pH Meter Method | Prepare an aqueous solution at a specified concentration (e.g., 1% w/v) and measure its acidity using a calibrated pH meter, reflecting the acidic nature of the sample due to the carboxylic acid group. |
| Boron Content | Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) or Titration | ICP-OES accurately determines total boron content; alternatively, boron in the boronic acid group can be indirectly measured via complexation with mannitol followed by titration with a standard NaOH solution. |
| Water Content | Karl Fischer Titration | Utilize Karl Fischer reagent to quantitatively react with water in the sample; moisture content is precisely determined via coulometric or volumetric methods, suitable for trace water analysis. |
| Test Item | Specification |
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| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 245-249°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.