Bis(trimethylsilyl)trifluoroacetamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 25561-30-2 |
| Product name | Bis(trimethylsilyl)trifluoroacetamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Bis(trimethylsilyl)trifluoroacetamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Bis(trimethylsilyl)trifluoroacetamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Bis(trimethylsilyl)trifluoroacetamide
| Industry | Application | Process |
|---|---|---|
| Analytical Chemistry | Derivatization reagent for gas chromatography analysis | Used to form silylated derivatives with hydroxyl, carboxyl, or amino groups |
| Pharmaceutical Industry | Pharmaceutical intermediate and synthetic building block | Used in organic synthesis to introduce silyl protecting groups |
| Agrochemical Industry | Intermediate for synthesizing fluorinated pesticides | Applied in fluorination derivatization reactions |
| Materials Science | Synthesis of organosilicon materials | Applied in silylation reactions |
| Biochemistry | Sample pretreatment for biological matrices to enhance detection sensitivity | Used to protect and modify reactive functional groups in samples |
Manufacturing Quality Control of Bis(trimethylsilyl)trifluoroacetamide
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Content) | Gas Chromatography (GC) | Uses a capillary gas chromatograph (GC) with internal or external standard method to determine the main component content of BSTFA. Purity is calculated by comparing retention times with reference standards and integrating peak areas. Commonly employs FID or MS detectors. |
| Moisture Content | Karl Fischer Titration | Quantifies trace water in the sample through a stoichiometric reaction with Karl Fischer reagent. The endpoint is detected by titration, making it suitable for low-moisture samples. This is the standard method for determining moisture in organic reagents. |
| Acidity (Acid Value) | Acid-Base Titration (Potentiometric or Visual) | Titrates acidic impurities in the sample using a standard alkaline solution. The endpoint is determined potentiometrically or by indicator, assessing the level of acidic impurities and reflecting product stability. |
| Residual Solvents | Gas Chromatography-Mass Spectrometry (GC-MS) | Analyzes potential residual organic solvents (e.g., methanol, dichloromethane) using selected ion monitoring (SIM) mode to enhance sensitivity and specificity, ensuring compliance with ICH Q3A/B guidelines. |
| Silylation Capability (Activity Test) | Fourier Transform Infrared Spectroscopy (FTIR) | Analyzes characteristic absorption peaks (e.g., Si–CH₃ at 1250–1300 cm⁻¹, C=O at 1750–1800 cm⁻¹) via FTIR to confirm the integrity of the trifluoroacetamide group, evaluating its effectiveness as a derivatization reagent. |
| Residue on Ignition / Inorganic Impurities | Gravimetric Method after High-Temperature Ashing | The sample is incinerated at high temperature, and the residue is weighed to assess levels of inorganic salts or contaminants such as metal ions. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Determines heavy metal elements such as lead, cadmium, mercury, and arsenic using AAS or ICP-MS, ensuring concentrations are below pharmacopeial or industrial limits (e.g., USP <233>). |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (¹H NMR, ¹³C NMR) | Analyzes characteristic signals in ¹H NMR and ¹³C NMR spectra (e.g., TMS group peaks, chemical shifts of CF₃ and C=O groups) to confirm molecular structure identity. |
| Thermal Stability | Differential Scanning Calorimetry (DSC) | Measures thermal behaviors such as melting point and decomposition temperature of BSTFA to evaluate its thermal stability during storage and use. |
Technical Specifications of Bis(trimethylsilyl)trifluoroacetamide
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.410–1.430 |
| Relative Density (20°C/25°C) | 0.96–0.99 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Bis(trimethylsilyl)trifluoroacetamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Bis(trimethylsilyl)trifluoroacetamide
Safety Information of Bis(trimethylsilyl)trifluoroacetamide
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of Bis(trimethylsilyl)trifluoroacetamide
Industrial Bis(trimethylsilyl)trifluoroacetamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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