3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 25629-50-9 |
| Product name | 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
| Industry | Application | Process Description |
|---|---|---|
| Pesticides | Insecticide intermediate | Used as a key intermediate in the synthesis of pyrethroid insecticides, participating in acylation reactions to form the active ester structure |
| Pharmaceuticals | Drug synthesis intermediate | Applied in the synthesis of anti-inflammatory and antibacterial agents, enabling construction of isoxazole ring systems and benzamide derivatives |
| Chemical Industry | Organic synthesis reagent | Employed as an acid chloride reagent in organic synthesis for preparing amides and ester derivatives |
| Research & Development | New compound screening | Utilized as a structural building block for constructing and evaluating novel bioactive molecules |
Manufacturing Quality Control of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection Method | Observe the sample's color, physical state, and presence of foreign matter under natural light or standard illumination. The substance should typically appear as a white to off-white crystalline powder. |
| Identification | Infrared Spectroscopy (IR) High-Performance Liquid Chromatography (HPLC) |
IR: Measure the infrared absorption spectrum of the sample and compare it with the reference standard spectrum to confirm characteristic functional groups (e.g., acyl chloride, isoxazole ring); HPLC: Confirm structural identity based on consistent retention time under specific chromatographic conditions. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with mobile phases such as methanol-water or acetonitrile-water. Detect using a UV detector (typically 220–254 nm), and calculate the main component content by external standard method. Purity is generally required to be ≥98.0%. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient or isocratic elution programs to separate and detect potential process impurities (e.g., unreacted starting materials, hydrolysis products such as 3-(2-chlorophenyl)-5-methyl-4-isoxazoleacetic acid) and degradation products. Impurity levels are calculated using area normalization or correction factor methods. |
| Moisture | Karl Fischer Titration | Determine water content using either the volumetric or coulometric Karl Fischer method. This is critical for controlling moisture risk due to the hygroscopic nature of the acyl chloride group. Typically, moisture must be ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace injection or direct injection with polar or non-polar capillary columns and FID detection to measure residual organic solvents (e.g., dichloromethane, toluene, DMF) from synthesis processes, complying with ICH Q3C guidelines. |
| Melting Point | Capillary Melting Point Method | Determine the melting temperature range using a melting point apparatus as a physical constant for auxiliary identification. The typical melting point range is approximately 85–90°C (specific value may vary according to literature or official standards). |
| pH Value (if formulated into solution) | pH Meter Method | Dissolve the sample in an appropriate inert solvent system (e.g., acetone/water mixture) and measure pH. This provides indirect indication of hydrolysis level (acyl chloride hydrolysis produces acidic byproducts, leading to decreased pH). |
Technical Specifications of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85–89°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
Safety Information of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride
Industrial 3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply