2,3-Dichlorothiophene-5-sulfonamide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 256353-34-1 |
| Product name | 2,3-Dichlorothiophene-5-sulfonamide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,3-Dichlorothiophene-5-sulfonamide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,3-Dichlorothiophene-5-sulfonamide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,3-Dichlorothiophene-5-sulfonamide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of β-lactamase inhibitors (e.g., Relebactam) | Serves as a key intermediate in coupling or condensation reactions |
| Pharmaceuticals | Intermediate for antibacterial agents | Used to construct drug molecule scaffolds containing thiophene moieties |
| Chemicals | Raw material for organic synthesis | Used to prepare more complex sulfonamide derivatives |
Manufacturing Quality Control of 2,3-Dichlorothiophene-5-sulfonamide
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances (Impurities) | HPLC-UV or UPLC-MS | Separation and detection of structurally related impurities (e.g., mono-chloro analogs, des-sulfonyl, hydrolysis products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., dichloromethane, methanol, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, using isotopic detection for high sensitivity and selectivity. |
| Sulfated Ash | Gravimetric Analysis (Weight Loss on Ignition) | Residue mass after incineration at 500–600 °C following sulfuric acid treatment, indicating inorganic impurities. |
| Chloride Content | Ion Chromatography (IC) or Potentiometric Titration | Anion exchange separation with conductivity detection (IC), or argentometric titration with AgNO₃ endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate. |
| Appearance & Color | Visual Inspection / Hazen (APHA) Scale | Subjective assessment of crystallinity and color intensity compared to platinum-cobalt standards. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volumetric particle size distribution in dry or wet dispersion. |
| Bulk & Tapped Density | ASTM D6393 (Powder Rheology Tester) | Measurement of mass per unit volume before and after standardized mechanical tapping to assess flowability and compaction behavior. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | pH determination of a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Sulfonamide Group Integrity | FTIR Spectroscopy | Identification of characteristic S=O asymmetric/symmetric stretches (~1350 cm⁻¹ and ~1150 cm⁻¹) and N–H stretch (~3300 cm⁻¹). |
Technical Specifications of 2,3-Dichlorothiophene-5-sulfonamide
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.3% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,3-Dichlorothiophene-5-sulfonamide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
Safety Information of 2,3-Dichlorothiophene-5-sulfonamide
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,3-Dichlorothiophene-5-sulfonamide
Industrial 2,3-Dichlorothiophene-5-sulfonamide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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