China Factory Direct
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| CAS number | 25637-16-5 |
| Product name | 4-BROMO-TETRAHYDROPYRAN |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates | Used to synthesize brominated heterocyclic drug molecules |
| Agrochemicals | Preparation of agrochemical intermediates | Introduces a brominated tetrahydropyran moiety to enhance biological activity |
| Fine chemicals | Synthesis of functional organic compounds | Participates in cyclization, substitution, and other reaction steps |
| Materials science | Monomer preparation | Monomer modification in polymer synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies 4-bromotetrahydropyran relative to internal or external standard using retention time and peak area comparison. |
| Related Substances | Gas Chromatography (GC) with FID detector | Detects and quantifies structurally similar impurities (e.g., isomers, dehydrohalogenation products) based on relative retention times and response factors. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents (e.g., dichloromethane, toluene) by equilibrium partitioning into headspace followed by GC separation. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Determines trace water via electrochemical generation of iodine and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Acidity (as HBr) | Acid-Base Titration with NaOH | Neutralizes acidic impurities (e.g., residual HBr) using standardized sodium hydroxide solution and potentiometric or indicator endpoint detection. |
| Color | Visual Comparison against APHA Scale | Evaluates yellowness/browning by comparing sample appearance in a Nessler tube to standardized platinum-cobalt reference solutions. |
| Density at 20 C | Digital Density Meter (Oscillating U-tube) | Measures mass per unit volume via resonant frequency shift of a vibrating U-shaped glass tube filled with sample. |
| Refractive Index at 20 C | Digital Refractometer | Determines light bending angle at air-sample interface using total internal reflection principle and calibrated prism system. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separates and quantifies chloride ions after sample dissolution and dilution, using anion-exchange column and suppressed conductivity detection. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Atomizes and ionizes digested sample; detects elemental isotopes based on mass-to-charge ratio with high sensitivity and multi-element capability. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measures non-volatile inorganic residue after controlled high-temperature ashing of sample and subsequent weighing. |
| Optical Rotation | [alpha]D at 20 C | Measures specific rotation of plane-polarized light using sodium D-line source and temperature-controlled cell to confirm chiral integrity and enantiomeric consistency. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.515–1.525 |
| Relative Density (20°C/25°C) | 1.42–1.46 g/cm³ |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.