(R)-Phenylglycine tert-butyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 256478-95-2 |
| Product name | (R)-Phenylglycine tert-butyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for (R)-Phenylglycine tert-butyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-Phenylglycine tert-butyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-Phenylglycine tert-butyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing β-lactam antibiotics (e.g., cephalosporins, penicillin derivatives) | Used in asymmetric synthesis, chiral resolution, and condensation reactions |
| Pharmaceuticals | Synthesis of D-phenylglycine derivatives for manufacturing semi-synthetic antibiotics | Applied in multi-step organic synthesis, including esterification, deprotection, and amidation |
| Chemical Research | Chiral source or chiral auxiliary for asymmetric catalysis research | Employed in constructing reaction systems such as catalytic hydrogenation, nucleophilic substitution, and cycloaddition |
Manufacturing Quality Control of (R)-Phenylglycine tert-butyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, relative to a certified reference standard. |
| Chiral Purity (enantiomeric excess) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak areas. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection, quantifying common solvents (e.g., EtOAc, MeOH, DCM) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Ion | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection with standard calibration. |
| Residual tert-Butyl Alcohol | GC-FID | Direct injection GC-FID analysis targeting residual t-BuOH, using external calibration curve. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free acid content. |
| Loss on Drying (LOD) | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum conditions for specified time. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine D10, D50, D90 values. |
| Microbial Contamination | Membrane Filtration | Filtration of dissolved sample followed by incubation on appropriate media to detect aerobic microorganisms. |
| Appearance and Color | Visual Inspection & Hazen Color Scale | Comparison of dissolved sample solution against platinum-cobalt standards under controlled lighting. |
Technical Specifications of (R)-Phenylglycine tert-butyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to yellow solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -72.0 to -67.0 deg (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 98.0 to 102.0 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of (R)-Phenylglycine tert-butyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-Phenylglycine tert-butyl ester hydrochloride
Safety Information of (R)-Phenylglycine tert-butyl ester hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-Phenylglycine tert-butyl ester hydrochloride
Industrial (R)-Phenylglycine tert-butyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply