China Factory Direct
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| CAS number | 2565-47-1 |
| Product name | N-METHYLBARBITURIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing barbiturate sedative-hypnotic drugs (e.g., meprobamate) | N-alkylation with alkyl halides (e.g., chloromethane) under basic conditions |
| Organic Synthesis | Building block for heterocyclic compound synthesis | Participates in cycloaddition, condensation, and other reactions to prepare pyrimidine and triazine derivatives |
| Pesticides | Synthesis intermediate for certain insecticides and plant growth regulators | Multi-step functionalization—including acylation and amination—to introduce bioactive structures |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration | Quantifies 1-methylbarbituric acid by titration with standardized sodium hydroxide using phenolphthalein indicator; based on acidic proton neutralization. |
| Moisture Content | Karl Fischer Titration | Determines water content via coulometric or volumetric reaction between water and iodine in pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic impurities by ignition at 700-800 C and weighing residual ash. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) | Quantifies lead, cadmium, mercury, and arsenic after acid digestion by measuring atomic absorption at element-specific wavelengths. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Barium Sulfate Gravimetry | Precipitates sulfate as BaSO4 under controlled pH and temperature, followed by filtration and weighing. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Separates and quantifies structurally related impurities using reversed-phase C18 column and UV detection at 210 nm. |
| Melting Point | Capillary Melting Point Determination | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP/Ph. Eur. guidelines. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode and pH meter. |
| Organic Volatile Impurities | Gas Chromatography (GC) with FID | Detects and quantifies residual solvents (e.g., methanol, acetone) using capillary column separation and flame ionization detection. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Measures mass loss upon heating to 105 C for 2 hours, indicating volatile components including residual solvents and moisture. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light by chiral impurities or enantiomeric excess in solution using sodium D-line. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 172–176°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.