5-Chloroindoline Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 25658-80-4 |
| Product name | 5-Chloroindoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Chloroindoline
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Chloroindoline Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Chloroindoline
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Synthetic intermediate | Used to prepare biologically active indole derivatives as structural motifs for antitumor, anti-inflammatory, or neuromodulatory agents |
| Organic synthesis | Construction of nitrogen-containing heterocyclic scaffolds | Functional groups are introduced via electrophilic substitution or transition metal-catalyzed coupling reactions for total synthesis of complex molecules |
| Agrochemical chemistry | Intermediate for agrochemical active ingredients | Involved in the synthesis of heterocyclic compounds with insecticidal, fungicidal, or herbicidal activity |
| Materials science | Design of functional molecules | Serves as a precursor for nitrogen-containing aromatic rings in optoelectronic materials or organic semiconductors, enabling molecular structure modification |
Manufacturing Quality Control of 5-Chloroindoline
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification/quantification of structurally related impurities (e.g., 5-chloroindole, indoline, chlorinated isomers) using gradient elution and diode-array or mass-spectrometric detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Heavy Metals (Total) | ICP-OES | Multi-element quantification of catalyst-derived metals (e.g., Pd, Ni, Fe) after acid digestion, based on atomic emission intensity at element-specific wavelengths. |
| Moisture Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water content via iodine generation and stoichiometric reaction with water in anhydrous methanol-based reagent. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid–liquid phase transition temperature using controlled heating and visual observation of sample collapse/fusion. |
| Chloride Ion (Inorganic Chloride) | Ion Chromatography (IC) with Conductivity Detection | Separation of chloride anions on an anion-exchange column and quantification by conductivity response relative to calibration standards. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (crystalline solid) and color intensity compared against platinum-cobalt standard solutions. |
| Specific Optical Rotation | [α]D Measurement (Polarimetry) | Measurement of rotation angle of plane-polarized light at 589 nm to confirm enantiomeric purity (if chiral synthesis route employed). |
Technical Specifications of 5-Chloroindoline
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 68.0 - 72.0 °C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Chloroindoline
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Chloroindoline
Packaging of 5-Chloroindoline
Industrial 5-Chloroindoline Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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