H-ARG(PBF)-OME HCL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 257288-19-0 |
| Product name | H-ARG(PBF)-OME HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 5KG/bag25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for H-ARG(PBF)-OME HCL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk H-ARG(PBF)-OME HCL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of H-ARG(PBF)-OME HCL
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Amino acid protecting reagent for peptide drug synthesis | Used as a side-chain protecting group for arginine in solid-phase peptide synthesis (SPPS); the guanidino group is masked with the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) moiety; supplied as the hydrochloride salt to ensure stable crystalline form for accurate weighing and long-term storage; deprotection performed using a trifluoroacetic acid (TFA)-based cleavage system |
| Pharmaceuticals | Building block for therapeutic peptide intermediates (e.g., anticoagulant and immunomodulatory peptides) | Employed in Fmoc-based strategies alongside Fmoc-Arg(Pbf)-OH for linear peptide chain elongation, ensuring chemical stability of the arginine residue during coupling and final cleavage steps |
Manufacturing Quality Control of H-ARG(PBF)-OME HCL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 200-220 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally similar impurities using gradient elution and UV absorbance; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, ethyl acetate) based on retention time and peak area. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Inductively coupled plasma mass spectrometry for simultaneous quantification of trace metal impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to detect endpoint based on change in potential due to AgCl precipitation. |
| Specific Optical Rotation | [alpha]D Measurement | Measurement of rotation of plane-polarized light at 589 nm using sodium D-line to confirm chiral integrity and enantiomeric purity. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Direct measurement using calibrated glass electrode in a defined aqueous solution (e.g., 1% w/v) to assess acidity from hydrochloride salt dissociation. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight to determine inorganic ash content as percent by weight. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering pattern to calculate volume-based particle size distribution (D10, D50, D90). |
| Microbial Limits | Membrane Filtration | Filtration of solution through sterile membrane followed by incubation on selective agar media to enumerate total aerobic microbes and detect specified pathogens. |
| Counterion (HCl) Content | Acid-Base Titration | Back-titration with standardized NaOH after addition of excess NaOH, using phenolphthalein or potentiometric endpoint detection. |
Technical Specifications of H-ARG(PBF)-OME HCL
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Optical Rotation | +12.0 to +14.0° (c=1, 6M HCl) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of H-ARG(PBF)-OME HCL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of H-ARG(PBF)-OME HCL
Packaging of H-ARG(PBF)-OME HCL
Industrial H-ARG(PBF)-OME HCL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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