PHTHALOYL-L-GLUTAMIC ANHYDRIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 25830-77-7 |
| Product name | PHTHALOYL-L-GLUTAMIC ANHYDRIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for PHTHALOYL-L-GLUTAMIC ANHYDRIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk PHTHALOYL-L-GLUTAMIC ANHYDRIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in synthesizing L-glutamic acid derivatives, such as the prodrug of the antiepileptic drug lacosamide | Undergoes ring-opening acylation with amines under anhydrous conditions, followed by hydrolysis and purification to yield the target product |
| Organic Synthesis | Used as a chiral protecting group reagent for selective protection of the α-amino and γ-carboxyl groups of L-glutamic acid | Cyclized via dehydration with acetic anhydride/sodium acetate under inert atmosphere at low temperature (0–5 °C), then applied for amino group protection in peptide synthesis |
| Materials Science | Used as a functional monomer in constructing chiral polymers or liquid crystalline materials | Incorporated into polymers via ring-opening polymerization (ROP) or condensation with diols/diamines to introduce chiral side chains, thereby modulating optical activity and self-assembly behavior |
Manufacturing Quality Control of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by reverse-phase HPLC with UV detection at 210-230 nm using a calibrated standard curve. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection relative to main peak area. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents (e.g., DMF, toluene) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent to determine trace water based on stoichiometric reaction. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Sulfated Ash | Gravimetric Analysis | Incineration at 600-750 C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering to determine volume-weighted particle size distribution. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to agar media, and colony counting after incubation. |
Technical Specifications of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 175–179 °C |
| Optical Rotation | -44.0 to -41.0 ° (c=1, in DMF) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
Safety Information of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of PHTHALOYL-L-GLUTAMIC ANHYDRIDE
Industrial PHTHALOYL-L-GLUTAMIC ANHYDRIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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