China Factory Direct
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| CAS number | 2592-19-0 |
| Product name | BOC-LYS(BOC)-ONP |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Side-chain protecting reagent for lysine residues in peptide synthesis | Used in solid-phase peptide synthesis (SPPS) to selectively protect the ε-amino group of lysine and prevent side reactions; the Boc group is cleaved under acidic conditions (e.g., TFA), while ONP (p-nitrophenol) serves as an activated leaving group to facilitate subsequent coupling |
| Biochemistry | Modification intermediate for structural and functional studies of proteins/peptides | Used to prepare site-specifically modified peptide probes—such as fluorescent or biotinylated precursors—via efficient amine coupling using the ONP-activated ester |
| Organic Synthesis | Building block for unnatural amino acid derivatives and pharmaceutical molecules | Employed as a chiral synthon in total synthesis of complex molecules, e.g., for introducing side-chain functionality in anticancer peptide drugs (such as precursors to certain histone deacetylase inhibitors) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by retention time and UV absorbance relative to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in pyridine/methanol medium. |
| Optical Rotation | Polarimetry | Determines specific rotation using plane-polarized light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) by atomic emission after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content after high-temperature incineration and weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and purity. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against established reference standards under controlled lighting. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in aqueous suspension or solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution of solid particles by measuring angular variation in scattered laser light intensity. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 124-128°C |
| Optical Rotation | -29.0 to -26.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.