China Factory Direct
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| CAS number | 26120-86-5 |
| Product name | 2,5-DIFLUOROBENZENESULFONYL CHLORIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Used as a fluorinated benzenesulfonylation reagent to synthesize sulfonamide- or sulfonylurea-based active pharmaceutical ingredients, introducing the 2,5-difluorobenzenesulfonyl group to enhance metabolic stability or biological activity. |
| Agrochemicals | Agrochemical Intermediate | Used to synthesize fluorinated benzenesulfonylurea herbicides or other sulfonamide-based insecticides and fungicides, leveraging its electron-withdrawing group to improve efficacy. |
| Organic Synthesis | Introduction of Protecting Groups for Alcohols and Amines | Applied as a sulfonylation reagent in multistep organic synthesis to react with alcohols or amines, forming corresponding sulfonate esters or sulfonamides for hydroxyl or amino group protection. |
| Dyes and Pigments | Fluorinated Dye Intermediate | Used to synthesize fluorinated azo dyes or fluorescent dyes; introduction of the sulfonyl chloride group improves color fastness, solubility, or hue properties. |
| Electronic Chemicals | Synthesis of Organic Optoelectronic Materials | Applied in synthesizing electron-transport or hole-blocking materials for organic light-emitting diodes (OLEDs) and organic photovoltaics, where the fluorinated structure facilitates energy-level tuning. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| 2,5-Difluorobenzenesulfonyl Chloride Identity | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirmation via characteristic absorption bands, especially S=O stretch (~1370 cm-1) and C-F stretch (~1100 cm-1). |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detection and quantification of volatile organic solvents (e.g., dichloromethane, toluene) using headspace sampling and GC-FID. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine reacts stoichiometrically with water in anhydrous methanol-based reagent. |
| Acid Value | Acid-Base Titration (NaOH in isopropanol/water) | Neutralization of acidic impurities (e.g., hydrolyzed sulfonyl chloride) with standardized NaOH solution using phenolphthalein indicator. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Separation of Cl- anions on an anion-exchange column followed by quantitative detection via suppressed conductivity. |
| Heavy Metals (Pb, Cd, Hg, As) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Multi-element detection after microwave-assisted acid digestion, based on elemental mass-to-charge ratios. |
| Non-Volatile Residue | Gravimetric Analysis (Weight Loss on Drying) | Evaporation of sample under controlled temperature and vacuum, followed by weighing of residual solids. |
| Color (APHA) | Visual Comparison or Spectrophotometric Measurement (APHA scale) | Comparison of sample solution color intensity against platinum-cobalt standards at 455 nm wavelength. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature using calibrated capillary tube method per USP <741>. |
| Sulfate Impurity | Barium Sulfate Gravimetric Method | Precipitation of sulfate as BaSO4 in acidic medium, followed by filtration, drying, and weighing. |
| Organic Impurities (Related Substances) | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation on reversed-phase C18 column; detection at 220 nm and 254 nm to identify and quantify structurally related compounds. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Conforms to reference standard |
| Melting Point | -15 to -10°C |
| Refractive Index (n20/D) | 1.535–1.545 |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.