(R)-N-Boc-3-Bromophenylalanine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 261360-77-4 |
| Product name | (R)-N-Boc-3-Bromophenylalanine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-N-Boc-3-Bromophenylalanine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-N-Boc-3-Bromophenylalanine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-N-Boc-3-Bromophenylalanine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Synthesis of peptide-based drugs | Serves as a non-natural amino acid monomer; the D-phenylalanine moiety is incorporated via solid-phase peptide synthesis (SPPS) or solution-phase synthesis to prepare biologically active peptides (e.g., side-chain-modified therapeutics). |
| Pharmaceutical Industry | Drug discovery and screening | Used to construct non-natural peptide libraries; D-configured and brominated side chains enable screening for candidate drug molecules with enhanced metabolic stability or improved target-binding specificity. |
| Organic Synthesis | Preparation of organic intermediates | Leverages the reactivity of the bromine atom in metal-catalyzed coupling processes—including Suzuki, Heck, and Sonogashira couplings—to introduce aryl, alkenyl, or alkynyl groups onto the phenyl ring. |
| Biochemistry | Protein structure and function studies | Functions as a probe molecule; chemically incorporated into proteins or peptides to investigate protein folding, molecular interactions, and structure–activity relationships using the spectroscopic properties or crosslinking capability of bromophenylalanine. |
| Materials Science | Fabrication of functional materials | Employed in synthesizing peptide-based materials with tailored optoelectronic properties or self-assembly behavior; halogen bonding modulates their physicochemical characteristics. |
Manufacturing Quality Control of (R)-N-Boc-3-Bromophenylalanine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, methanol, ethyl acetate) using flame ionization detection with headspace sampling. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample via light scattering pattern to determine D10, D50, D90 values. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Boc, hydrolyzed, dimeric species) using gradient reversed-phase HPLC. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride anion on an anion-exchange column with suppressed conductivity detection. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic mesophilic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
Technical Specifications of (R)-N-Boc-3-Bromophenylalanine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | +15.0° to +19.0° (c=1, in 1M HCl) |
| Identification (NMR) | Conforms to reference standard |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-N-Boc-3-Bromophenylalanine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-N-Boc-3-Bromophenylalanine
Safety Information of (R)-N-Boc-3-Bromophenylalanine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-N-Boc-3-Bromophenylalanine
Industrial (R)-N-Boc-3-Bromophenylalanine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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