China Factory Direct
|
|
| CAS number | 26156-48-9 |
| Product name | 2-BROMO-ISONICOTINIC ACID METHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of anticancer, antiviral, or central nervous system drugs | Used to construct pyridine-containing bioactive molecules via nucleophilic substitution and coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Agrochemicals | Structural building block for synthesizing novel insecticides or herbicides | Integrated into the core agrochemical structure via halogen exchange, ester hydrolysis, or further functional group transformations |
| Materials Science | Precursor for organic optoelectronic materials (e.g., OLED emissive layers or electron-transport materials) | Employed to build conjugated systems via metal-catalyzed cross-coupling reactions, enabling control over energy levels and charge-carrier mobility |
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Utilizes reversed-phase chromatographic columns with mobile phases of methanol/water or acetonitrile/water, and UV detection (e.g., 254 nm) to quantify the main component's purity and assess impurity levels. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Performs ¹H NMR and ¹³C NMR analyses to examine chemical shifts of hydrogen and carbon atoms, confirming molecular structure and substitution positions in accordance with the target compound. |
| Molecular Weight Confirmation | Mass Spectrometry (MS) | Employs electrospray ionization (ESI) or electron impact (EI) MS to determine molecular ion peaks ([M+H]⁺ or M⁺), verifying molecular weight and fragmentation patterns. |
| Impurity Identification and Quantification | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines HPLC separation capability with MS identification power to deduce structures and perform relative quantification of unknown impurities, particularly suitable for trace byproduct analysis. |
| Water Content | Karl Fischer Titration | Uses volumetric or coulometric methods to determine trace water content in samples, ensuring product dryness meets storage and reaction requirements. |
| Residual Solvents | Gas Chromatography (GC) | Employs headspace or direct injection with FID detection to analyze residual organic solvents (e.g., methanol, dichloromethane), complying with ICH Q3C limits. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Measures the temperature range at which a substance transitions from solid to liquid, serving as a physical constant to assist in assessing purity and crystal form consistency. |
| Appearance and Color | Visual Color Comparison Method | Observes the appearance of solids or solutions under standard lighting conditions (e.g., white to off-white crystalline), checking for foreign matter or abnormal discoloration to preliminarily evaluate product quality. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Performs trace-level detection of elements such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopeial or client-specific limits for metal impurities. |
| Chiral Purity (if applicable) | Chiral High-Performance Liquid Chromatography | If chiral centers are present, chiral columns are used to separate enantiomers and assess optical purity (ee value); however, this compound contains no chiral centers, making this test typically not applicable. |
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.