tert-butyl 5-bromoindoline-1-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 261732-38-1 |
| Product name | tert-butyl 5-bromoindoline-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for tert-butyl 5-bromoindoline-1-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk tert-butyl 5-bromoindoline-1-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of tert-butyl 5-bromoindoline-1-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an intermediate for synthesizing indoline-based pharmaceuticals in the development of anticancer, antiviral, and neurotherapeutic agents | Introduces aromatic groups via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, or Negishi coupling) on N-BOC-protected 5-bromoindoline, followed by Boc deprotection to construct the target molecular structure |
| Organic Synthesis | Used as a versatile organic synthesis intermediate for constructing nitrogen-containing heterocyclic compounds | Enables functional group transformation via nucleophilic substitution or metal-catalyzed cross-coupling reactions using the bromine atom, with selective modification facilitated by the Boc protecting group |
| Biomedical Research | Used to construct novel small-molecule probes or fluorescently labeled compounds for target identification and drug screening | Leverages the chemical reactivity of the bromine atom to conjugate fluorescent dyes or bioactive fragments, enabling functionalized molecule construction |
| Materials Science | Used as a functionalized monomer precursor for designing organic materials with tailored optical or electronic properties | Undergoes graft modification in polymerization reactions via its bromine atom and amine group, enhancing solubility and enabling precise property tuning |
Manufacturing Quality Control of tert-butyl 5-bromoindoline-1-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient HPLC with UV detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Qualitative and quantitative analysis of volatile organic solvents based on retention time matching and calibration curves using flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent; water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residues using inductively coupled plasma optical emission spectrometry after microwave-assisted digestion. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to assess chiral purity and identity of enantiomeric form. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern to calculate volume-based particle size distribution in dispersed powder samples. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile and moisture content. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection with carbonate/bicarbonate eluent. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence testing for specified pathogens using standardized culture media and incubation conditions. |
Technical Specifications of tert-butyl 5-bromoindoline-1-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of tert-butyl 5-bromoindoline-1-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of tert-butyl 5-bromoindoline-1-carboxylate
Safety Information of tert-butyl 5-bromoindoline-1-carboxylate
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of tert-butyl 5-bromoindoline-1-carboxylate
Industrial tert-butyl 5-bromoindoline-1-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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