5-CHLORO-2-FLUOROPHENYLACETIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 261762-97-4 |
| Product name | 5-CHLORO-2-FLUOROPHENYLACETIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-CHLORO-2-FLUOROPHENYLACETIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-CHLORO-2-FLUOROPHENYLACETIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for the synthesis of the antidiabetic drug sitagliptin | Produces the (S)-configured key intermediate via asymmetric catalytic hydrogenation or enzymatic reduction of 5-chloro-2-fluorophenylacetic acid derivatives (e.g., corresponding ketones or imines), followed by multistep construction of the triazolopiperazine ring |
| Agrochemicals | Structural building block for novel herbicides and fungicides | Serves as a fluorinated arylacetic acid lead compound, participating in coupling reactions (e.g., Suzuki, Heck) to introduce heterocycles or functionalized side chains, thereby optimizing target activity and metabolic stability |
| Materials | Functionalized precursor for liquid crystal monomers and organic optoelectronic materials | Introduces alkoxy, cyano, or vinyl groups at specific positions on the benzene ring via esterification, halogen exchange, or palladium-catalyzed C–H activation to tune molecular birefringence and dielectric anisotropy |
Manufacturing Quality Control of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 220-254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-DAD or HPLC-MS | Separation and identification of impurities based on retention time and spectral/mass data; quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated standards. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis after acid digestion; detection at sub-ppq levels using mass spectrometry. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Moisture Content | Karl Fischer Coulometric Titration | Electrochemical generation of titrant (I2) proportional to water content; precise quantification for low moisture levels (< 0.1%). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; onset and range indicate crystallinity and purity. |
| Optical Rotation | [alpha]D Measurement | Polarimetric determination of specific rotation at 589 nm to confirm chiral integrity (if applicable) and detect racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity vs. angle to derive volume-based particle size distribution in dry or wet dispersion. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode to assess acidic character and salt formation. |
| Sulfated Ash | Gravimetric Analysis | High-temperature incineration followed by sulfuric acid treatment and final weighing to determine inorganic residue content. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized mechanical tapping to assess flowability and handling characteristics. |
Technical Specifications of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 220-235 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
Safety Information of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-CHLORO-2-FLUOROPHENYLACETIC ACID
Industrial 5-CHLORO-2-FLUOROPHENYLACETIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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