4-Methyl-3-(trifluoromethyl)benzoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 261952-01-6 |
| Product name | 4-Methyl-3-(trifluoromethyl)benzoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-3-(trifluoromethyl)benzoic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-3-(trifluoromethyl)benzoic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-3-(trifluoromethyl)benzoic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing the side-chain structure of the antidiabetic drug sitagliptin | Multistep organic synthesis, including asymmetric catalytic hydrogenation, amidation, and hydrolysis |
| Agrochemicals | Structural building block for herbicides and fungicides; used in developing novel trifluoromethylbenzoic acid-based agroactive ingredients | Halogenation, trifluoromethylation, carboxyl group protection/deprotection, and coupling reactions |
| Materials Science | Building block for liquid crystal monomers and functional materials for organic light-emitting diodes (OLEDs) | Fine chemical synthesis, including esterification, Suzuki coupling, and palladium-catalyzed arylation |
Manufacturing Quality Control of 4-Methyl-3-(trifluoromethyl)benzoic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~230 nm. |
| Related Substances (Impurities) | HPLC-UV with Gradient Elution | Separation and quantification of structurally related impurities (e.g., isomers, dehalogenated analogs, residual starting materials) using optimized gradient RP-HPLC and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantitative analysis of toxic elements (Pb, Cd, Hg, As) after acid digestion, offering sub-pptr detection limits and compliance with ICH Q3D. |
| Chloride Content | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection, suitable for low-level inorganic halide impurity assessment. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water content via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; deviation from literature value (148–150 °C) indicates polymorphic or impurity-related anomalies. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Determination of non-volatile inorganic residue after high-temperature ashing (700–800 °C) followed by precise weighing. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at sodium D-line (589 nm) to confirm chiral purity — though compound is achiral, this detects potential chiral contaminants or degradation products. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie theory to determine D10, D50, D90 values relevant for downstream processing (e.g., filtration, formulation). |
Technical Specifications of 4-Methyl-3-(trifluoromethyl)benzoic acid
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Acid Value (mg KOH/g) | 320–340 mg KOH/g |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-3-(trifluoromethyl)benzoic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-3-(trifluoromethyl)benzoic acid
Safety Information of 4-Methyl-3-(trifluoromethyl)benzoic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Methyl-3-(trifluoromethyl)benzoic acid
Industrial 4-Methyl-3-(trifluoromethyl)benzoic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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