China Factory Direct
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| CAS number | 261953-36-0 |
| Product name | 6-Iodo-1H-indazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a synthetic pharmaceutical intermediate for constructing bioactive compounds, including antitumor and anti-inflammatory agents | Indazole scaffolds are introduced via coupling reactions (e.g., Suzuki or Stille coupling) to enable molecular structure modification |
| Organic Synthesis | Used as a precursor for functionalized heterocyclic compounds | The high reactivity of the iodine atom enables cross-coupling or nucleophilic substitution reactions to construct complex molecular architectures |
| Materials Science | Applied in the development of novel optoelectronic materials or fluorescent probes | Iodo groups participate in polymerization or functionalization to modulate electronic properties and luminescence characteristics |
| Biochemical Research | Used as a biologically active molecular probe for target identification and mechanistic studies | Protein or enzyme functional states are tracked via covalent binding or reversible labeling techniques |
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Identification | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with reference spectra to confirm characteristic functional groups and structure of 6-Iodo-1H-indazole. |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Use NMR technology to analyze chemical shifts, coupling constants, and other properties of hydrogen atoms in the molecule to verify compound structure. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Perform reversed-phase HPLC using a C18 column and UV detector (e.g., 254 nm) for quantification; calculate active ingredient content by external standard method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Using the same conditions as assay or optimized gradient elution, separate and detect potential organic impurities (e.g., starting materials, by-products, degradation products); control limits using area normalization or main component self-dilution method with correction factors. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with polar or non-polar capillary columns and FID detector; control common organic solvents (e.g., methanol, dichloromethane, DMF) according to pharmacopoeial limits. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Drying Method | Dry the sample at specified temperature (e.g., 105°C) until constant weight; calculate percentage weight loss to assess moisture and volatile content. |
| Melting Point | Melting Point Determination | Determine the melting range (from initial to complete melting) using capillary tube method or digital melting point apparatus as an auxiliary indicator of purity and identity. |
| Water Content | Karl Fischer Titration (KF) | Apply KF titration to accurately measure trace water content; suitable for moisture-sensitive intermediates or active pharmaceutical ingredients. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, determine total or individual elemental impurities such as lead, cadmium, mercury, arsenic, etc., in compliance with ICH Q3D requirements. |
| Test Item | Specification |
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| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 185–189 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.