China Factory Direct
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| CAS number | 2621932-34-9 |
| Product name | 1,3-Naphthalenediol, 7-fluoro-8-[2-[tris(1-methylethyl)silyl]ethynyl]- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Used as an intermediate in the synthesis of targeted therapeutics or fluorescent probe molecules | Acetylene group introduced via Sonogashira coupling, followed by deprotection or functionalization |
| Organic Synthesis | Construction of complex molecular scaffolds containing fluorinated naphthalene rings | Silyl-protected acetylene employed in cross-coupling or cyclization reactions; triisopropylsilyl (TIPS) serves as a cleavable protecting group |
| Materials Science | Potential use in designing fluorinated optoelectronic materials or ligands | Fluorine atoms and acetylene groups jointly modulate electronic properties; desilylation enables subsequent polymerization or coordination assembly |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at optimized wavelength based on absorbance of aromatic and alkyne chromophores. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., desilylated, hydrolyzed, or isomeric by-products) using gradient HPLC separation and UV response. |
| Residual Solvents | GC-FID | Identifies and quantifies volatile organic solvents (e.g., THF, toluene, IPA) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Pd) after acid digestion using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Residual Silicon | ICP-OES | Measures total silicon content from TIPS group degradation or reagent carryover using inductively coupled plasma optical emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions (from synthesis residues or HCl quenching) using suppressed conductivity detection after aqueous extraction. |
| Acid Value | Acid-Base Titration | Determines free acidic groups (e.g., phenolic OH) by titration with standardized NaOH solution using potentiometric or phenolphthalein endpoint detection. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid-to-liquid phase transition occurs, indicating crystallinity and presence of impurities affecting lattice integrity. |
| Bulk Density | USP <616> Method I | Determines mass per unit volume of freely settled powder using calibrated cylinder and balance, relevant for handling and formulation consistency. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of dry powder via scattering pattern analysis of laser beam passed through dispersed sample in air stream. |
| Residual Palladium | ICP-MS | Quantifies palladium catalyst residue from Sonogashira coupling step using high-sensitivity ICP-MS after microwave-assisted acid digestion. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.